Assessing skin sensitization hazard in mice and men using non-animal test methods D Urbisch, A Mehling, K Guth, T Ramirez, N Honarvar, S Kolle, ... Regulatory Toxicology and Pharmacology 71 (2), 337-351, 2015 | 353 | 2015 |
Development of an in vitro skin sensitization test using human cell lines: The human Cell Line Activation Test (h-CLAT): I. Optimization of the h-CLAT protocol T Ashikaga, Y Yoshida, M Hirota, K Yoneyama, H Itagaki, H Sakaguchi, ... Toxicology in vitro 20 (5), 767-773, 2006 | 339 | 2006 |
Development of an in vitro skin sensitization test using human cell lines; human Cell Line Activation Test (h-CLAT) II. An inter-laboratory study of the h-CLAT H Sakaguchi, T Ashikaga, M Miyazawa, Y Yoshida, Y Ito, K Yoneyama, ... Toxicology in vitro 20 (5), 774-784, 2006 | 242 | 2006 |
Categorization of chemicals according to their relative human skin sensitizing potency DA Basketter, N Alépée, T Ashikaga, J Barroso, N Gilmour, C Goebel, ... Dermatitis 25 (1), 11-21, 2014 | 216 | 2014 |
Non-animal methods to predict skin sensitization (II): an assessment of defined approaches NC Kleinstreuer, S Hoffmann, N Alépée, D Allen, T Ashikaga, W Casey, ... Critical reviews in toxicology 48 (5), 359-374, 2018 | 167 | 2018 |
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database S Hoffmann, N Kleinstreuer, N Alépée, D Allen, AM Api, T Ashikaga, ... Critical reviews in toxicology 48 (5), 344-358, 2018 | 152 | 2018 |
Systematic evaluation of non-animal test methods for skin sensitisation safety assessment K Reisinger, S Hoffmann, N Alépée, T Ashikaga, J Barroso, C Elcombe, ... Toxicology in Vitro 29 (1), 259-270, 2015 | 151 | 2015 |
A Comparative Evaluation of In Vitro Skin Sensitisation Tests: The Human Cell-line Activation Test (h-CLAT) versus the Local Lymph Node Assay (LLNA) T Ashikaga, H Sakaguchi, S Sono, N Kosaka, M Ishikawa, Y Nukada, ... Alternatives to laboratory animals 38 (4), 275-284, 2010 | 148 | 2010 |
Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy JS Jaworska, A Natsch, C Ryan, J Strickland, T Ashikaga, M Miyazawa Archives of toxicology 89, 2355-2383, 2015 | 145 | 2015 |
Effect of the photocatalytic activity of TiO2 on plasmid DNA T Ashikaga, M Wada, H Kobayashi, M Mori, Y Katsumura, H Fukui, S Kato, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 466 (1), 1-7, 2000 | 125 | 2000 |
The relationship between CD86/CD54 expression and THP-1 cell viability in an in vitro skin sensitization test–human cell line activation test (h-CLAT) H Sakaguchi, T Ashikaga, M Miyazawa, N Kosaka, Y Ito, K Yoneyama, ... Cell biology and toxicology 25, 109-126, 2009 | 120 | 2009 |
Evaluation of CD86 expression and MHC class II molecule internalization in THP-1 human monocyte cells as predictive endpoints for contact sensitizers T Ashikaga, M Hoya, H Itagaki, Y Katsumura, S Aiba Toxicology in Vitro 16 (6), 711-716, 2002 | 118 | 2002 |
Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency Y Nukada, T Ashikaga, M Miyazawa, M Hirota, H Sakaguchi, H Sasa, ... Toxicology in vitro 26 (7), 1150-1160, 2012 | 115 | 2012 |
Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and … O Takenouchi, S Fukui, K Okamoto, S Kurotani, N Imai, M Fujishiro, ... Journal of Applied Toxicology 35 (11), 1318-1332, 2015 | 102 | 2015 |
Identifying and characterizing chemical skin sensitizers without animal testing: Colipa’s research and method development program P Aeby, T Ashikaga, S Bessou-Touya, A Schepky, F Gerberick, P Kern, ... Toxicology in vitro 24 (6), 1465-1473, 2010 | 92 | 2010 |
Predictive performance for human skin sensitizing potential of the human cell line activation test (h‐CLAT) Y Nukada, T Ashikaga, H Sakaguchi, S Sono, N Mugita, M Hirota, ... Contact dermatitis 65 (6), 343-353, 2011 | 86 | 2011 |
Predictive performance of the human Cell Line Activation Test (h-CLAT) for lipophilic chemicals with high octanol-water partition coefficients O Takenouchi, M Miyazawa, K Saito, T Ashikaga, H Sakaguchi The Journal of toxicological sciences 38 (4), 599-609, 2013 | 76 | 2013 |
Predicting skin sensitization potential and inter-laboratory reproducibility of a human Cell Line Activation Test (h-CLAT) in the European Cosmetics Association (COLIPA) ring … H Sakaguchi, C Ryan, JM Ovigne, KR Schroeder, T Ashikaga Toxicology in Vitro 24 (6), 1810-1820, 2010 | 70 | 2010 |
Evaluation of combinations of in vitro sensitization test descriptors for the artificial neural network‐based risk assessment model of skin sensitization M Hirota, S Fukui, K Okamoto, S Kurotani, N Imai, M Fujishiro, D Kyotani, ... Journal of Applied Toxicology 35 (11), 1333-1347, 2015 | 59 | 2015 |
Skin sensitisation: the Colipa strategy for developing and evaluating non-animal test methods for risk assessment G Maxwell, P Aeby, T Ashikaga, S Bessou-Touya, W Diembeck, ... ALTEX-Alternatives to animal experimentation 28 (1), 50-55, 2011 | 56 | 2011 |