| APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function X Mao, CK Kikani, RA Riojas, P Langlais, L Wang, FJ Ramos, Q Fang, ... Nature cell biology 8 (5), 516-523, 2006 | 844 | 2006 |
| Adiponectin signaling and function in insulin target tissues H Ruan, LQ Dong Journal of molecular cell biology 8 (2), 101-109, 2016 | 442 | 2016 |
| APPL1: role in adiponectin signaling and beyond SS Deepa, LQ Dong American Journal of Physiology-Endocrinology and Metabolism 296 (1), E22-E36, 2009 | 377 | 2009 |
| Adiponectin sensitizes insulin signaling by reducing p70 S6 kinase-mediated serine phosphorylation of IRS-1 C Wang, X Mao, L Wang, M Liu, MD Wetzel, KL Guan, LQ Dong, F Liu Journal of Biological Chemistry 282 (11), 7991-7996, 2007 | 293 | 2007 |
| Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent … L Zhou, SS Deepa, JC Etzler, J Ryu, X Mao, Q Fang, DD Liu, JM Torres, ... Journal of Biological Chemistry 284 (33), 22426-22435, 2009 | 263 | 2009 |
| A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization M Liu, L Zhou, A Xu, KSL Lam, MD Wetzel, R Xiang, J Zhang, X Xin, ... Proceedings of the National Academy of Sciences 105 (47), 18302-18307, 2008 | 261 | 2008 |
| DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway J Bai, C Cervantes, J Liu, S He, H Zhou, B Zhang, H Cai, D Yin, D Hu, Z Li, ... Proceedings of the National Academy of Sciences 114 (46), 12196-12201, 2017 | 211 | 2017 |
| PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle LQ Dong, F Liu American journal of physiology-Endocrinology and Metabolism 289 (2), E187-E196, 2005 | 206 | 2005 |
| Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR M Liu, SA Wilk, A Wang, L Zhou, RH Wang, W Ogawa, C Deng, LQ Dong, ... Journal of Biological Chemistry 285 (47), 36387-36394, 2010 | 193 | 2010 |
| Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1 MJ Wick, LQ Dong, RA Riojas, FJ Ramos, F Liu Journal of Biological Chemistry 275 (51), 40400-40406, 2000 | 182 | 2000 |
| Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells C Wang, X Xin, R Xiang, FJ Ramos, M Liu, HJ Lee, H Chen, X Mao, ... Journal of Biological Chemistry 284 (46), 31608-31615, 2009 | 174 | 2009 |
| Peripheral disruption of the Grb10 gene enhances insulin signaling and sensitivity in vivo L Wang, B Balas, CY Christ-Roberts, RY Kim, FJ Ramos, CK Kikani, C Li, ... Molecular and cellular biology 27 (18), 6497-6505, 2007 | 164 | 2007 |
| Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the … KLR Wick, ED Werner, P Langlais, FJ Ramos, LQ Dong, SE Shoelson, ... Journal of Biological Chemistry 278 (10), 8460-8467, 2003 | 159 | 2003 |
| Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton LQ Dong, LR Landa, MJ Wick, L Zhu, H Mukai, Y Ono, F Liu Proceedings of the National Academy of Sciences 97 (10), 5089-5094, 2000 | 138 | 2000 |
| DsbA-L alleviates endoplasmic reticulum stress–induced adiponectin downregulation L Zhou, M Liu, J Zhang, H Chen, LQ Dong, F Liu Diabetes 59 (11), 2809-2816, 2010 | 134 | 2010 |
| Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance L Zhou, J Zhang, Q Fang, M Liu, X Liu, W Jia, LQ Dong, F Liu Molecular pharmacology 76 (3), 596-603, 2009 | 134 | 2009 |
| Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1 Q Tu, J Zhang, LQ Dong, E Saunders, E Luo, J Tang, J Chen Journal of Biological Chemistry 286 (14), 12542-12553, 2011 | 133 | 2011 |
| APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor J Ryu, AK Galan, X Xin, F Dong, MA Abdul-Ghani, L Zhou, C Wang, C Li, ... Cell reports 7 (4), 1227-1238, 2014 | 128 | 2014 |
| Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Cζ LQ Dong, R Zhang, P Langlais, H He, M Clark, L Zhu, F Liu Journal of Biological Chemistry 274 (12), 8117-8122, 1999 | 125 | 1999 |
| Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1 M Liu, J Bai, S He, R Villarreal, D Hu, C Zhang, X Yang, H Liang, TJ Slaga, ... Cell metabolism 19 (6), 967-980, 2014 | 124 | 2014 |
Meilian LiuUniversity of New Mexico Health Sciences CenterVerified email at salud.unm.edu
