PPARγ activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties MA Bouhlel, B Derudas, E Rigamonti, R Dièvart, J Brozek, S Haulon, ... Cell metabolism 6 (2), 137-143, 2007 | 1560 | 2007 |
Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXRα pathways G Chinetti-Gbaguidi, M Baron, MA Bouhlel, J Vanhoutte, C Copin, Y Sebti, ... Circulation research 108 (8), 985-995, 2011 | 440 | 2011 |
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma B Lamprecht, K Walter, S Kreher, R Kumar, M Hummel, D Lenze, ... Nature medicine 16 (5), 571-579, 2010 | 384 | 2010 |
Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages E Rigamonti, L Helin, S Lestavel, AL Mutka, M Lepore, C Fontaine, ... Circulation research 97 (7), 682-689, 2005 | 162 | 2005 |
Unlike PPARγ, PPARα or PPARβ/δ activation does not promote human monocyte differentiation toward alternative macrophages MA Bouhlel, J Brozek, B Derudas, C Zawadzki, B Jude, B Staels, ... Biochemical and biophysical research communications 386 (3), 459-462, 2009 | 72 | 2009 |
Peroxisome proliferator‐activated receptors–from active regulators of macrophage biology to pharmacological targets in the treatment of cardiovascular disease MA Bouhlel, B Staels, G Chinetti‐Gbaguidi Journal of internal medicine 263 (1), 28-42, 2008 | 67 | 2008 |
11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis T Kipari, PWF Hadoke, J Iqbal, TY Man, E Miller, AE Coutinho, Z Zhang, ... The FASEB journal 27 (4), 1519, 2013 | 65 | 2013 |
New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors C Gros, L Fleury, V Nahoum, C Faux, S Valente, D Labella, F Cantagrel, ... Journal of Biological Chemistry 290 (10), 6293-6302, 2015 | 62 | 2015 |
Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma S Kreher, MA Bouhlel, P Cauchy, B Lamprecht, S Li, M Grau, F Hummel, ... Proceedings of the National Academy of Sciences 111 (42), E4513-E4522, 2014 | 62 | 2014 |
Rational design of bisubstrate-type analogues as inhibitors of DNA methyltransferases in cancer cells L Halby, Y Menon, E Rilova, D Pechalrieu, V Masson, C Faux, MA Bouhlel, ... Journal of Medicinal Chemistry 60 (11), 4665-4679, 2017 | 46 | 2017 |
Targeting transcription factor binding to DNA by competing with DNA binders as an approach for controlling gene expression M Amine Bouhlel, M Lambert, MH David-Cordonnier Current topics in medicinal chemistry 15 (14), 1323-1358, 2015 | 45 | 2015 |
Visfatin is induced by peroxisome proliferator‐activated receptor gamma in human macrophages TH Mayi, C Duhem, C Copin, MA Bouhlel, E Rigamonti, F Pattou, B Staels, ... The FEBS journal 277 (16), 3308-3320, 2010 | 44 | 2010 |
Peroxisome Proliferator–Activated Receptor-γ Activation Induces 11β-Hydroxysteroid Dehydrogenase Type 1 Activity in Human Alternative Macrophages G Chinetti-Gbaguidi, MA Bouhlel, C Copin, C Duhem, B Derudas, B Neve, ... Arteriosclerosis, thrombosis, and vascular biology 32 (3), 677-685, 2012 | 43 | 2012 |
Perilipin, a potential substitute for adipophilin in triglyceride storage in human macrophages G Larigauderie, MA Bouhlel, C Furman, M Jaye, JC Fruchart, M Rouis Atherosclerosis 189 (1), 142-148, 2006 | 33 | 2006 |
The Function of the Conserved Regulatory Element within the Second Intron of the Mammalian Csf1r Locus KA Sauter, MA Bouhlel, J O’Neal, DP Sester, H Tagoh, RM Ingram, ... PloS one 8 (1), e54935, 2013 | 32 | 2013 |
Differential regulation of sense and antisense promoter activity at the Csf1R locus in B cells by the transcription factor PAX5 RM Ingram, S Valeaux, N Wilson, MA Bouhlel, D Clarke, I Krüger, D Kulu, ... Experimental hematology 39 (7), 730-740. e2, 2011 | 8 | 2011 |
Glitazones in the treatment of cardiovascular risk factors MA Bouhlel, G Chinetti‐Gbaguidi, B Staels Fundamental & clinical pharmacology 21, 7-13, 2007 | 5 | 2007 |
HOXA9 transcription factor as a target in acute myeloid leukemia: Transcription, cellular and in vivo consequences of its invalidation M Lambert, S Jambon, S Depauw, MA Bouhlel, M Figeac, ... European Journal of Cancer 1 (69), S23, 2016 | 1 | 2016 |
Targeting transcription factor at the DNA binding level: Inhibition of ERG and FLI1 binding to their consensus DNA binding site R Nhili, S Depauw, M Lambert, MA Bouhlel, MH David-Cordonnier INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 34, S16-S16, 2014 | | 2014 |
The Function of the Conserved Regulatory Element within the Second Intron of the KA Sauter, MA Bouhlel, J O’Neal, DP Sester, H Tagoh | | 2013 |