Maria Rosalia Pasca
Maria Rosalia Pasca
Dept. Biology and Biotechnology "L. Spallanzani", UNIVERSITY OF PAVIA
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Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis
V Makarov, G Manina, K Mikusova, U Möllmann, O Ryabova, ...
Science 324 (5928), 801-804, 2009
Global Analysis of the Mycobacterium tuberculosis Zur (FurB) Regulon
A Maciag, E Dainese, GM Rodriguez, A Milano, R Provvedi, MR Pasca, ...
Journal of bacteriology 189 (3), 730-740, 2007
Rv2686c-Rv2687c-Rv2688c, an ABC Fluoroquinolone Efflux Pump in Mycobacterium tuberculosis
MR Pasca, P Guglierame, F Arcesi, M Bellinzoni, E De Rossi, G Riccardi
Antimicrobial agents and chemotherapy 48 (8), 3175-3178, 2004
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212
V La Rosa, G Poce, JO Canseco, S Buroni, MR Pasca, M Biava, RM Raju, ...
Antimicrobial agents and chemotherapy 56 (1), 324-331, 2012
mmpL7 Gene of Mycobacterium tuberculosis Is Responsible for Isoniazid Efflux in Mycobacterium smegmatis
MR Pasca, P Guglierame, E De Rossi, F Zara, G Riccardi
Antimicrobial agents and chemotherapy 49 (11), 4775-4777, 2005
Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5–MmpL5 efflux system
A Milano, MR Pasca, R Provvedi, AP Lucarelli, G Manina, ALJL Ribeiro, ...
Tuberculosis 89 (1), 84-90, 2009
Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-d-ribofuranose 2′-Oxidase DprE1
C Trefzer, H Škovierová, S Buroni, A Bobovská, S Nenci, E Molteni, ...
Journal of the American Chemical Society 134 (2), 912-915, 2012
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis
J Neres, F Pojer, E Molteni, LR Chiarelli, N Dhar, S Boy-Röttger, S Buroni, ...
Science translational medicine 4 (150), 150ra121-150ra121, 2012
Clinical Isolates of Mycobacterium tuberculosis in Four European Hospitals Are Uniformly Susceptible to Benzothiazinones
MR Pasca, G Degiacomi, ALJL Ribeiro, F Zara, P De Mori, B Heym, ...
Antimicrobial agents and chemotherapy 54 (4), 1616-1618, 2010
Efflux pump genes of the resistance-nodulation-division family in Burkholderia cenocepacia genome
P Guglierame, MR Pasca, E De Rossi, S Buroni, P Arrigo, G Manina, ...
BMC microbiology 6 (1), 1-14, 2006
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1
J Neres, RC Hartkoorn, LR Chiarelli, R Gadupudi, MR Pasca, G Mori, ...
ACS chemical biology 10 (3), 705-714, 2015
Synthesis and biological activities of triazole derivatives as inhibitors of InhA and antituberculosis agents
C Menendez, S Gau, C Lherbet, F Rodriguez, C Inard, MR Pasca, ...
European journal of medicinal chemistry 46 (11), 5524-5531, 2011
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection
G Poce, RH Bates, S Alfonso, M Cocozza, GC Porretta, L Ballell, J Rullas, ...
PloS one 8 (2), e56980, 2013
Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents
C Menendez, A Chollet, F Rodriguez, C Inard, MR Pasca, C Lherbet, ...
European journal of medicinal chemistry 52, 275-283, 2012
The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis
G Riccardi, MR Pasca, LR Chiarelli, G Manina, A Mattevi, C Binda
Applied microbiology and biotechnology 97 (20), 8841-8848, 2013
Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepaciain intrinsic antibiotic resistance
S Buroni, MR Pasca, RS Flannagan, S Bazzini, A Milano, I Bertani, ...
BMC microbiology 9 (1), 1-11, 2009
Characterization and Heterologous Expression of the Oxalyl Coenzyme A Decarboxylase Gene from Bifidobacterium lactis
F Federici, B Vitali, R Gotti, MR Pasca, S Gobbi, AB Peck, P Brigidi
Applied and Environmental Microbiology 70 (9), 5066-5073, 2004
Mycobacterium tuberculosis: drug resistance and future perspectives
G Riccardi, MR Pasca, S Buroni
Future microbiology 4 (5), 597-614, 2009
Deciphering the role of RND efflux transporters in Burkholderia cenocepacia
S Bazzini, C Udine, A Sass, MR Pasca, F Longo, G Emiliani, M Fondi, ...
PloS one 6 (4), e18902, 2011
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance
G Manina, M Bellinzoni, MR Pasca, J Neres, A Milano, ...
Molecular microbiology 77 (5), 1172-1185, 2010
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