Iain Tan
Iain Tan
Senior Consultant Medical Oncologist & Clinician Scientist, National Cancer Centre Singapore
Bestätigte E-Mail-Adresse bei nccs.com.sg
Titel
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Jahr
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes
ZJ Zang, I Cutcutache, SL Poon, SL Zhang, JR McPherson, J Tao, ...
Nature genetics 44 (5), 570-574, 2012
5982012
A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets
N Deng, LK Goh, H Wang, K Das, J Tao, IB Tan, S Zhang, M Lee, J Wu, ...
Gut 61 (5), 673-684, 2012
5552012
Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors
H Li, ET Courtois, D Sengupta, Y Tan, KH Chen, JJL Goh, SL Kong, ...
Nature genetics 49 (5), 708-718, 2017
4272017
Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates
Y Simoni, E Becht, M Fehlings, CY Loh, SL Koo, KWW Teng, JPS Yeong, ...
Nature 557 (7706), 575-579, 2018
3932018
Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers
W Chan-On, ML Nairismägi, CK Ong, WK Lim, S Dima, C Pairojkul, ...
Nature genetics 45 (12), 1474, 2013
3482013
Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil
Z Lei, IB Tan, K Das, N Deng, H Zouridis, S Pattison, C Chua, Z Feng, ...
Gastroenterology 145 (3), 554-565, 2013
3102013
Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy
IB Tan, T Ivanova, KH Lim, CW Ong, N Deng, J Lee, SH Tan, J Wu, ...
Gastroenterology 141 (2), 476-485. e11, 2011
3082011
Oncogenic pathway combinations predict clinical prognosis in gastric cancer
CH Ooi, T Ivanova, J Wu, M Lee, IB Tan, J Tao, L Ward, JH Koo, ...
PLoS Genet 5 (10), e1000676, 2009
3072009
Paradoxical relationship between chromosomal instability and survival outcome in cancer
NJ Birkbak, AC Eklund, Q Li, SE McClelland, D Endesfelder, P Tan, ...
Cancer research 71 (10), 3447-3452, 2011
2852011
Human innate lymphoid cell subsets possess tissue-type based heterogeneity in phenotype and frequency
Y Simoni, M Fehlings, HN Kløverpris, N McGovern, SL Koo, CY Loh, ...
Immunity 46 (1), 148-161, 2017
2572017
Pan-Asian adapted ESMO consensus guidelines for the management of patients with metastatic colorectal cancer: a JSMO–ESMO initiative endorsed by CSCO, KACO, MOS, SSO and TOS
T Yoshino, D Arnold, H Taniguchi, G Pentheroudakis, K Yamazaki, RH Xu, ...
Annals of Oncology 29 (1), 44-70, 2018
2112018
The prevalence of menopausal symptoms in a community in Singapore
H Chim, BHI Tan, CC Ang, EMD Chew, YS Chong, SM Saw
Maturitas 41 (4), 275-282, 2002
2072002
Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer
HK Oh, ALK Tan, K Das, CH Ooi, NT Deng, IBH Tan, E Beillard, J Lee, ...
Clinical cancer research 17 (9), 2657-2667, 2011
1932011
First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE …
HS Wasan, P Gibbs, NK Sharma, J Taieb, V Heinemann, J Ricke, ...
The Lancet Oncology 18 (9), 1159-1171, 2017
1902017
Methylation subtypes and large-scale epigenetic alterations in gastric cancer
H Zouridis, N Deng, T Ivanova, Y Zhu, B Wong, D Huang, YH Wu, Y Wu, ...
Science translational medicine 4 (156), 156ra140-156ra140, 2012
1692012
Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas
SJ Lin, JA Gagnon-Bartsch, IB Tan, S Earle, L Ruff, K Pettinger, B Ylstra, ...
Gut 64 (11), 1721-1731, 2015
1582015
Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia
T Fukawa, BC Yan-Jiang, JC Min-Wen, ET Jun-Hao, D Huang, CN Qian, ...
Nature medicine 22 (6), 666-671, 2016
1202016
Comprehensive genomic meta-analysis identifies intra-tumoural stroma as a predictor of survival in patients with gastric cancer
Y Wu, H Grabsch, T Ivanova, IB Tan, J Murray, CH Ooi, AI Wright, NP West, ...
Gut 62 (8), 1100-1111, 2013
1152013
Risk of hepatitis B virus (HBV) reactivation in hepatitis B surface antigen negative/hepatitis B core antibody positive patients receiving rituximab-containing combination …
YX Koo, M Tay, YE Teh, D Teng, DSW Tan, IBH Tan, DWM Tai, R Quek, ...
Annals of hematology 90 (10), 1219-1223, 2011
1122011
Hepatitis B virus reactivation and role of antiviral prophylaxis in lymphoma patients with past hepatitis B virus infection who are receiving chemoimmunotherapy
YX Koo, DSW Tan, IB Tan, M Tao, WC Chow, ST Lim
Cancer: Interdisciplinary International Journal of the American Cancer …, 2010
1022010
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