Natural products in drug discovery: advances and opportunities AG Atanasov, SB Zotchev, VM Dirsch, CT Supuran Nature reviews Drug discovery 20 (3), 200-216, 2021 | 1484 | 2021 |
Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 728 | 2015 |
Bacterial metabolism of long-chain n-alkanes A Wentzel, TE Ellingsen, HK Kotlar, SB Zotchev, M Throne-Holst Applied microbiology and biotechnology 76, 1209-1221, 2007 | 509 | 2007 |
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway T Brautaset, ON Sekurova, H Sletta, TE Ellingsen, AR Strøm, S Valla, ... Chemistry & biology 7 (6), 395-403, 2000 | 323 | 2000 |
Identification of Novel Genes Involved in Long-Chain n-Alkane Degradation by Acinetobacter sp. Strain DSM 17874 M Throne-Holst, A Wentzel, TE Ellingsen, HK Kotlar, SB Zotchev Applied and environmental microbiology 73 (10), 3327-3332, 2007 | 310 | 2007 |
Polyene macrolide antibiotics and their applications in human therapy SB Zotchev Current medicinal chemistry 10 (3), 211-223, 2003 | 304 | 2003 |
Actinomycetes from sediments in the Trondheim fjord, Norway: diversity and biological activity H Bredholt, E Fjærvik, G Johnsen, SB Zotchev Marine drugs 6 (1), 12-24, 2008 | 289 | 2008 |
Rare actinomycete bacteria from the shallow water sediments of the Trondheim fjord, Norway: isolation, diversity and biological activity H Bredholdt, OA Galatenko, K Engelhardt, E Fjærvik, LP Terekhova, ... Environmental microbiology 9 (11), 2756-2764, 2007 | 254 | 2007 |
Marine actinomycetes as an emerging resource for the drug development pipelines SB Zotchev Journal of biotechnology 158 (4), 168-175, 2012 | 214 | 2012 |
Production of a New Thiopeptide Antibiotic, TP-1161, by a Marine Nocardiopsis Species K Engelhardt, KF Degnes, M Kemmler, H Bredholt, E Fjærvik, ... Applied and environmental microbiology 76 (15), 4969-4976, 2010 | 213 | 2010 |
Polyene antibiotic biosynthesis gene clusters JF Aparicio, P Caffrey, JA Gil, SB Zotchev Applied microbiology and biotechnology 61, 179-188, 2003 | 183 | 2003 |
In Vivo Analysis of the Regulatory Genes in the Nystatin Biosynthetic Gene Cluster of Streptomyces noursei ATCC 11455 Reveals Their Differential Control Over … ON Sekurova, T Brautaset, H Sletta, SEF Borgos, ØM Jakobsen, ... Journal of bacteriology 186 (5), 1345-1354, 2004 | 138 | 2004 |
Violacein-Producing Collimonas sp. from the Sea Surface Microlayer of Costal Waters in Trøndelag, Norway S Hakvåg, E Fjærvik, G Klinkenberg, SEF Borgos, KD Josefsen, ... Marine drugs 7 (4), 576-588, 2009 | 102 | 2009 |
Biosynthetic engineering of polyene macrolides towards generation of improved antifungal and antiparasitic agents P Caffrey, JF Aparicio, F Malpartida, SB Zotchev Current topics in medicinal chemistry 8 (8), 639-653, 2008 | 101 | 2008 |
Novel bioactive natural products from bacteria via bioprospecting, genome mining and metabolic engineering ON Sekurova, O Schneider, SB Zotchev Microbial biotechnology 12 (5), 828-844, 2019 | 100 | 2019 |
Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei E Fjærvik, SB Zotchev Applied microbiology and biotechnology 67, 436-443, 2005 | 92 | 2005 |
Improved Antifungal Polyene Macrolides via Engineering of the Nystatin Biosynthetic Genes in Streptomyces noursei T Brautaset, H Sletta, A Nedal, SEF Borgos, KF Degnes, I Bakke, ... Chemistry & biology 15 (11), 1198-1206, 2008 | 89 | 2008 |
New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp. MP131-18 C Paulus, Y Rebets, B Tokovenko, S Nadmid, LP Terekhova, ... Scientific reports 7 (1), 1-11, 2017 | 83 | 2017 |
Chemical Diversity of Polyene Macrolides Produced by Streptomyces noursei ATCC 11455 and Recombinant Strain ERD44 with Genetically Altered Polyketide … P Bruheim, SEF Borgos, P Tsan, H Sletta, TE Ellingsen, JM Lancelin, ... Antimicrobial agents and chemotherapy 48 (11), 4120-4129, 2004 | 79 | 2004 |
Structure-antifungal activity relationships of polyene antibiotics of the amphotericin B group AN Tevyashova, EN Olsufyeva, SE Solovieva, SS Printsevskaya, ... Antimicrobial agents and chemotherapy 57 (8), 3815-3822, 2013 | 78 | 2013 |