Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 499 | 2015 |
Bacterial metabolism of long-chain n-alkanes A Wentzel, TE Ellingsen, HK Kotlar, SB Zotchev, M Throne-Holst Applied microbiology and biotechnology 76 (6), 1209-1221, 2007 | 442 | 2007 |
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway T Brautaset, ON Sekurova, H Sletta, TE Ellingsen, AR Strøm, S Valla, ... Chemistry & biology 7 (6), 395-403, 2000 | 292 | 2000 |
Actinomycetes from sediments in the Trondheim fjord, Norway: diversity and biological activity H Bredholt, E Fjærvik, G Johnsen, SB Zotchev Marine drugs 6 (1), 12-24, 2008 | 251 | 2008 |
Identification of novel genes involved in long-chain n-alkane degradation by Acinetobacter sp. strain DSM 17874 M Throne-Holst, A Wentzel, TE Ellingsen, HK Kotlar, SB Zotchev Applied and environmental microbiology 73 (10), 3327-3332, 2007 | 246 | 2007 |
Polyene macrolide antibiotics and their applications in human therapy SB Zotchev Current medicinal chemistry 10 (3), 211-223, 2003 | 243 | 2003 |
Rare actinomycete bacteria from the shallow water sediments of the Trondheim fjord, Norway: isolation, diversity and biological activity H Bredholdt, OA Galatenko, K Engelhardt, E Fjærvik, LP Terekhova, ... Environmental microbiology 9 (11), 2756-2764, 2007 | 217 | 2007 |
Marine actinomycetes as an emerging resource for the drug development pipelines SB Zotchev Journal of biotechnology 158 (4), 168-175, 2012 | 180 | 2012 |
Production of a new thiopeptide antibiotic, TP-1161, by a marine Nocardiopsis species K Engelhardt, KF Degnes, M Kemmler, H Bredholt, E Fjærvik, ... Applied and environmental microbiology 76 (15), 4969-4976, 2010 | 172 | 2010 |
Polyene antibiotic biosynthesis gene clusters JF Aparicio, P Caffrey, JA Gil, SB Zotchev Applied microbiology and biotechnology 61 (3), 179-188, 2003 | 169 | 2003 |
In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic … ON Sekurova, T Brautaset, H Sletta, SEF Borgos, ØM Jakobsen, ... Journal of bacteriology 186 (5), 1345-1354, 2004 | 119 | 2004 |
Violacein-producing Collimonas sp. from the sea surface microlayer of costal waters in Trøndelag, Norway S Hakvåg, E Fjærvik, G Klinkenberg, SEF Borgos, KD Josefsen, ... Marine drugs 7 (4), 576-588, 2009 | 87 | 2009 |
Biosynthetic engineering of polyene macrolides towards generation of improved antifungal and antiparasitic agents P Caffrey, JF Aparicio, F Malpartida, SB Zotchev Current topics in medicinal chemistry 8 (8), 639-653, 2008 | 86 | 2008 |
Improved Antifungal Polyene Macrolides via Engineering of the Nystatin Biosynthetic Genes in Streptomyces noursei T Brautaset, H Sletta, A Nedal, SEF Borgos, KF Degnes, I Bakke, ... Chemistry & biology 15 (11), 1198-1206, 2008 | 83 | 2008 |
Chemical diversity of polyene macrolides produced by Streptomyces noursei ATCC 11455 and recombinant strain ERD44 with genetically altered polyketide synthase NysC P Bruheim, SEF Borgos, P Tsan, H Sletta, TE Ellingsen, JM Lancelin, ... Antimicrobial agents and chemotherapy 48 (11), 4120-4129, 2004 | 70 | 2004 |
Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei E Fjærvik, SB Zotchev Applied microbiology and biotechnology 67 (4), 436-443, 2005 | 69 | 2005 |
Insights into the evolution of macrolactam biosynthesis through cloning and comparative analysis of the biosynthetic gene cluster for a novel macrocyclic lactam, ML-449 H Jørgensen, KF Degnes, A Dikiy, E Fjærvik, G Klinkenberg, SB Zotchev Applied and environmental microbiology 76 (1), 283-293, 2010 | 68 | 2010 |
Utilization of n-alkanes by a newly isolated strain of Acinetobacter venetianus: the role of two AlkB-type alkane hydroxylases M Throne-Holst, S Markussen, A Winnberg, TE Ellingsen, HK Kotlar, ... Applied microbiology and biotechnology 72 (2), 353-360, 2006 | 66 | 2006 |
Genome-based bioprospecting of microbes for new therapeutics SB Zotchev, ON Sekurova, L Katz Current opinion in biotechnology 23 (6), 941-947, 2012 | 64 | 2012 |
Isolation and characterization of the gene cluster for biosynthesis of the thiopeptide antibiotic TP-1161 K Engelhardt, KF Degnes, SB Zotchev Applied and environmental microbiology 76 (21), 7093-7101, 2010 | 64 | 2010 |