| ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data K Wang, M Li, H Hakonarson Nucleic acids research 38 (16), e164-e164, 2010 | 13547 | 2010 |
| Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000 L Liu, HL Johnson, S Cousens, J Perin, S Scott, JE Lawn, I Rudan, ... The lancet 379 (9832), 2151-2161, 2012 | 5480 | 2012 |
| Biological, clinical and population relevance of 95 loci for blood lipids TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ... Nature 466 (7307), 707-713, 2010 | 4118 | 2010 |
| Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, ... The Lancet 380 (9841), 572-580, 2012 | 2624 | 2012 |
| New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ... Nature genetics 42 (2), 105-116, 2010 | 2574 | 2010 |
| Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, ... Nature 478 (7367), 103-109, 2011 | 2327 | 2011 |
| Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease H Schunkert, IR König, S Kathiresan, MP Reilly, TL Assimes, H Holm, ... Nature genetics 43 (4), 333-338, 2011 | 2241 | 2011 |
| Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ... Nature genetics 42 (7), 579-589, 2010 | 2196 | 2010 |
| PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data K Wang, M Li, D Hadley, R Liu, J Glessner, SFA Grant, H Hakonarson, ... Genome research 17 (11), 1665-1674, 2007 | 2039 | 2007 |
| A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants LG Fritsche, W Igl, JNC Bailey, F Grassmann, S Sengupta, ... Nature genetics 48 (2), 134-143, 2016 | 1502 | 2016 |
| Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants S Kathiresan, BF Voight, S Purcell, K Musunuru, D Ardissino, ... Nature genetics 41 (3), 334-341, 2009 | 1310 | 2009 |
| Pathway-based approaches for analysis of genomewide association studies K Wang, M Li, M Bucan The American Journal of Human Genetics 81 (6), 1278-1283, 2007 | 1046 | 2007 |
| Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease J Park, R Shrestha, C Qiu, A Kondo, S Huang, M Werth, M Li, J Barasch, ... Science 360 (6390), 758-763, 2018 | 961 | 2018 |
| Analysing biological pathways in genome-wide association studies K Wang, M Li, H Hakonarson Nature Reviews Genetics 11 (12), 843-854, 2010 | 934 | 2010 |
| Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction R Do, NO Stitziel, HH Won, AB Jĝrgensen, S Duga, P Angelica Merlini, ... Nature 518 (7537), 102-106, 2015 | 772 | 2015 |
| Meta-analysis and imputation refines the association of 15q25 with smoking quantity JZ Liu, F Tozzi, DM Waterworth, SG Pillai, P Muglia, L Middleton, ... Nature genetics 42 (5), 436-440, 2010 | 736 | 2010 |
| Bulk tissue cell type deconvolution with multi-subject single-cell expression reference X Wang, J Park, K Susztak, NR Zhang, M Li Nature communications 10 (1), 380, 2019 | 731 | 2019 |
| SAVER: gene expression recovery for single-cell RNA sequencing M Huang, J Wang, E Torre, H Dueck, S Shaffer, R Bonasio, JI Murray, ... Nature methods 15 (7), 539-542, 2018 | 695 | 2018 |
| Parental origin of sequence variants associated with complex diseases A Kong, V Steinthorsdottir, G Masson, G Thorleifsson, P Sulem, ... Nature 462 (7275), 868-874, 2009 | 667 | 2009 |
| A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium N Soranzo, TD Spector, M Mangino, B Kühnel, A Rendon, A Teumer, ... Nature genetics 41 (11), 1182-1190, 2009 | 622 | 2009 |
Hakon HakonarsonDirector, Center for Applied Genomics, CHOP, UPENNVerified email at email.chop.edu
