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Gerd K Wagner
Gerd K Wagner
Professor of Medicinal Chemistry and Chemical Biology, Queen's University Belfast
Bestätigte E-Mail-Adresse bei qub.ac.uk
Titel
Zitiert von
Zitiert von
Jahr
New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase
C Peifer, G Wagner, S Laufer
Current topics in medicinal chemistry 6 (2), 113-149, 2006
1782006
A survey of chemical methods for sugar-nucleotide synthesis
GK Wagner, T Pesnot, RA Field
Natural product reports 26 (9), 1172-1194, 2009
1762009
Studies on the anti-inflammatory activity of phytopharmaceuticals prepared from Arnica flowers
CA Klaas, G Wagner, S Laufer, S Sosa, R Della Loggia, U Bomme, ...
Planta medica 68 (05), 385-391, 2002
1672002
Small molecular anti‐cytokine agents
G Wagner, S Laufer
Medicinal research reviews 26 (1), 1-62, 2006
1392006
Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes
SA Laufer, GK Wagner, DA Kotschenreuther, W Albrecht
Journal of medicinal chemistry 46 (15), 3230-3244, 2003
1272003
Glycosyltransferases and their assays
GK Wagner, T Pesnot
ChemBioChem 11 (14), 1939-1949, 2010
1112010
Ones, Thiones, and N‐Oxides: An Exercise in Imidazole Chemistry
S Laufer, G Wagner, D Kotschenreuther
Angewandte Chemie International Edition 41 (13), 2290-2293, 2002
952002
Trypanosoma brucei: chemical evidence that cathepsin L is essential for survival and a relevant drug target
D Steverding, DW Sexton, X Wang, SS Gehrke, GK Wagner, CR Caffrey
International journal for parasitology 42 (5), 481-488, 2012
942012
Structural and mechanistic basis for a new mode of glycosyltransferase inhibition
T Pesnot, R Jørgensen, MM Palcic, GK Wagner
Nature chemical biology 6 (5), 321-323, 2010
942010
Imidazole inhibitors of cytokine release: probing substituents in the 2 position
SA Laufer, HG Striegel, GK Wagner
Journal of medicinal chemistry 45 (21), 4695-4705, 2002
872002
First small molecular inhibitors of T. brucei dolicholphosphate mannose synthase (DPMS), a validated drug target in African sleeping sickness
TK Smith, BL Young, H Denton, DL Hughes, GK Wagner
Bioorganic & medicinal chemistry letters 19 (6), 1749-1752, 2009
762009
From imidazoles to pyrimidines: new inhibitors of cytokine release
SA Laufer, GK Wagner
Journal of medicinal chemistry 45 (13), 2733-2740, 2002
682002
A facile two-step synthesis of 8-arylated guanosine mono-and triphosphates (8-aryl GXPs)
A Collier, G Wagner
Organic & Biomolecular Chemistry 4 (24), 4526-4532, 2006
652006
Novel derivatives of UDP-glucose: concise synthesis and fluorescent properties
T Pesnot, GK Wagner
Organic & Biomolecular Chemistry 6 (16), 2884-2891, 2008
622008
Rapid synthetic route toward structurally modified derivatives of cyclic adenosine 5 ‘-diphosphate ribose
GK Wagner, AH Guse, BVL Potter
The Journal of Organic Chemistry 70 (12), 4810-4819, 2005
602005
Inhibition of galactosyltransferases by a novel class of donor analogues
K Descroix, T Pesnot, Y Yoshimura, SS Gehrke, W Wakarchuk, MM Palcic, ...
Journal of Medicinal Chemistry 55 (5), 2015-2024, 2012
482012
Structural Determinants for N1/N7 Cyclization of Nicotinamide Hypoxanthine 5 ‘-Dinucleotide (NHD+) Derivatives by ADP-Ribosyl Cyclase from Aplysia californica: Ca2+-Mobilizing …
C Moreau, GK Wagner, K Weber, AH Guse, BVL Potter
Journal of medicinal chemistry 49 (17), 5162-5176, 2006
472006
Identification of Regioisomers in a Series of N-Substituted Pyridin-4-yl Imidazole Derivatives by Regiospecific Synthesis, GC/MS, and 1H NMR
GK Wagner, D Kotschenreuther, W Zimmermann, SA Laufer
The Journal of organic chemistry 68 (11), 4527-4530, 2003
472003
2′-Deoxy cyclic adenosine 5′-diphosphate ribose derivatives: importance of the 2′-hydroxyl motif for the antagonistic activity of 8-substituted cADPR derivatives
B Zhang, GK Wagner, K Weber, C Garnham, AJ Morgan, A Galione, ...
Journal of medicinal chemistry 51 (6), 1623-1636, 2008
442008
Beyond substrate analogues: new inhibitor chemotypes for glycosyltransferases
L Tedaldi, GK Wagner
MedChemComm 5 (8), 1106-1125, 2014
432014
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