Kevin H. Gardner
Kevin H. Gardner
Director, Structural Biology Initiative - CUNY Advanced Science Research Center; Professor
Bestätigte E-Mail-Adresse bei gc.cuny.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Structural basis of a phototropin light switch
SM Harper, LC Neil, KH Gardner
Science 301 (5639), 1541-1544, 2003
7902003
THE USE OF 2H, 13C, 15N MULTIDIMENSIONAL NMR GTO STUDY THE STRUCTURE AND DYNAMICS OF PROTEINS
KH Gardner, LE Kay
Annual review of biophysics and biomolecular structure 27 (1), 357-406, 1998
7261998
A robust and cost-effective method for the production of Val, Leu, Ile (δ1) methyl-protonated 15N-, 13C-, 2H-labeled proteins
NK Goto, KH Gardner, GA Mueller, RC Willis, LE Kay
Journal of biomolecular NMR 13 (4), 369-374, 1999
5551999
Evolutionary information for specifying a protein fold
M Socolich, SW Lockless, WP Russ, H Lee, KH Gardner, R Ranganathan
Nature 437 (7058), 512-518, 2005
4672005
White collar-1, a DNA binding transcription factor and a light sensor
Q He, P Cheng, Y Yang, L Wang, KH Gardner, Y Liu
Science 297 (5582), 840-843, 2002
4352002
Targeting renal cell carcinoma with a HIF-2 antagonist
W Chen, H Hill, A Christie, MS Kim, E Holloman, A Pavia-Jimenez, ...
Nature 539 (7627), 112-117, 2016
3782016
Selective methyl group protonation of perdeuterated proteins
MK Rosen, KH Gardner, RC Willis, WE Parris, T Pawson, LE Kay
Journal of molecular biology 263 (5), 627-636, 1996
3391996
Disruption of the LOV− Jα helix interaction activates phototropin kinase activity
SM Harper, JM Christie, KH Gardner
Biochemistry 43 (51), 16184-16192, 2004
3252004
Global folds of highly deuterated, methyl-protonated proteins by multidimensional NMR
KH Gardner, MK Rosen, LE Kay
Biochemistry 36 (6), 1389-1401, 1997
3121997
Production and incorporation of 15N, 13C, 2H (1H-δ1 methyl) isoleucine into proteins for multidimensional NMR studies
KH Gardner, LE Kay
Journal of the American Chemical Society 119 (32), 7599-7600, 1997
2891997
An optogenetic gene expression system with rapid activation and deactivation kinetics
LB Motta-Mena, A Reade, MJ Mallory, S Glantz, OD Weiner, KW Lynch, ...
Nature chemical biology 10 (3), 196-202, 2014
2532014
Solution NMR spectroscopy beyond 25 kDa
LE Kay, KH Gardner
Current opinion in structural biology 7 (5), 722-731, 1997
2351997
Structural basis for PAS domain heterodimerization in the basic helix–loop–helix-PAS transcription factor hypoxia-inducible factor
PJA Erbel, PB Card, O Karakuzu, RK Bruick, KH Gardner
Proceedings of the National Academy of Sciences 100 (26), 15504-15509, 2003
2292003
Allosteric inhibition of hypoxia inducible factor-2 with small molecules
TH Scheuermann, Q Li, HW Ma, J Key, L Zhang, R Chen, JA Garcia, ...
Nature chemical biology 9 (4), 271, 2013
2222013
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor
TH Scheuermann, DR Tomchick, M Machius, Y Guo, RK Bruick, ...
Proceedings of the National Academy of Sciences 106 (2), 450-455, 2009
2142009
Identification of small-molecule antagonists that inhibit an activator: coactivator interaction
JL Best, CA Amezcua, B Mayr, L Flechner, CM Murawsky, B Emerson, ...
Proceedings of the National Academy of Sciences 101 (51), 17622-17627, 2004
2032004
Structure of a bacterial BLUF photoreceptor: insights into blue light-mediated signal transduction
A Jung, T Domratcheva, M Tarutina, Q Wu, W Ko, RL Shoeman, ...
Proceedings of the National Academy of Sciences 102 (35), 12350-12355, 2005
1862005
PAS domain-mediated WC-1/WC-2 interaction is essential for maintaining the steady-state level of WC-1 and the function of both proteins in circadian clock and light responses …
P Cheng, Y Yang, KH Gardner, Y Liu
Molecular and Cellular Biology 22 (2), 517-524, 2002
1832002
Rationally improving LOV domain–based photoswitches
D Strickland, X Yao, G Gawlak, MK Rosen, KH Gardner, TR Sosnick
Nature methods 7 (8), 623-626, 2010
1782010
Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation
CA Amezcua, SM Harper, J Rutter, KH Gardner
Structure 10 (10), 1349-1361, 2002
1772002
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