Flavia Trettel
Flavia Trettel
Dep. Physiology and Pharmacology Sapienza University
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Dominant phenotypes produced by the HD mutation in STHdhQ111 striatal cells
F Trettel, D Rigamonti, P Hilditch-Maguire, VC Wheeler, AH Sharp, ...
Human molecular genetics 9 (19), 2799-2809, 2000
Episodic ataxia type 2 (EA2) and spinocerebellar ataxia type 6 (SCA6) due to CAG repeat expansion in the CACNA1A gene on chromosome 19p
C Jodice, E Mantuano, L Veneziano, F Trettel, G Sabbadini, ...
Human molecular genetics 6 (11), 1973-1978, 1997
Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice
S Gines, IS Seong, E Fossale, E Ivanova, F Trettel, JF Gusella, ...
Human molecular genetics 12 (5), 497-508, 2003
Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles
P Hilditch-Maguire, F Trettel, LA Passani, A Auerbach, F Persichetti, ...
Human molecular genetics 9 (19), 2789-2797, 2000
TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence
TR Brummelkamp, RM Kortlever, M Lingbeek, F Trettel, ME MacDonald, ...
Journal of Biological Chemistry 277 (8), 6567-6572, 2002
Complete loss of P/Q calcium channel activity caused by a CACNA1A missense mutation carried by patients with episodic ataxia type 2
S Guida, F Trettel, S Pagnutti, E Mantuano, A Tottene, L Veneziano, ...
The American Journal of Human Genetics 68 (3), 759-764, 2001
Chemokine fractalkine/CX3CL1 negatively modulates active glutamatergic synapses in rat hippocampal neurons
D Ragozzino, S Di Angelantonio, F Trettel, C Bertollini, L Maggi, C Gross, ...
Journal of Neuroscience 26 (41), 10488-10498, 2006
Ligand-independent CXCR2 dimerization
F Trettel, S Di Bartolomeo, C Lauro, M Catalano, MT Ciotti, C Limatola
Journal of Biological Chemistry 278 (42), 40980-40988, 2003
Fractalkine in the nervous system: neuroprotective or neurotoxic molecule?
C Lauro, M Catalano, F Trettel, C Limatola
Annals of the New York academy of sciences 1351 (1), 141-148, 2015
Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death
C Lauro, R Cipriani, M Catalano, F Trettel, G Chece, V Brusadin, ...
Neuropsychopharmacology 35 (7), 1550-1559, 2010
Expression of functional neurotransmitter receptors in Xenopus oocytes after injection of human brain membranes
R Miledi, F Eusebi, A Martínez-Torres, E Palma, F Trettel
Proceedings of the National Academy of Sciences 99 (20), 13238-13242, 2002
Two exon-skipping mutations as the molecular basis of succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria)
KL Chambliss, DD Hinson, F Trettel, P Malaspina, A Novelletto, C Jakobs, ...
The American Journal of Human Genetics 63 (2), 399-408, 1998
LTP impairment by fractalkine/CX3CL1 in mouse hippocampus is mediated through the activity of adenosine receptor type 3 (A3R)
L Maggi, F Trettel, M Scianni, C Bertollini, F Eusebi, BB Fredholm, ...
Journal of neuroimmunology 215 (1-2), 36-42, 2009
CXCL16/CXCR6 axis drives microglia/macrophages phenotype in physiological conditions and plays a crucial role in glioma
F Lepore, G D'Alessandro, F Antonangeli, A Santoro, V Esposito, ...
Frontiers in immunology 9, 2750, 2018
BDNF modulates GABAA receptors microtransplanted from the human epileptic brain to Xenopus oocytes
E Palma, G Torchia, C Limatola, F Trettel, A Arcella, G Cantore, ...
Proceedings of the National Academy of Sciences 102 (5), 1667-1672, 2005
Mutant huntingtin forms in vivo complexes with distinct context-dependent conformations of the polyglutamine segment
F Persichetti, F Trettel, CC Huang, C Fraefel, HTM Timmers, JF Gusella, ...
Neurobiology of disease 6 (5), 364-375, 1999
Chemokines: key molecules that orchestrate communication among neurons, microglia and astrocytes to preserve brain function
F Trettel, MA Di Castro, C Limatola
Neuroscience 439, 230-240, 2020
CXCL16 orchestrates adenosine A3 receptor and MCP-1/CCL2 activity to protect neurons from excitotoxic cell death in the CNS
M Rosito, C Deflorio, C Limatola, F Trettel
Journal of Neuroscience 32 (9), 3154-3163, 2012
Trasmembrane chemokines CX3CL1 and CXCL16 drive interplay between neurons, microglia and astrocytes to counteract pMCAO and excitotoxic neuronal death
M Rosito, C Lauro, G Chece, A Porzia, L Monaco, F Mainiero, M Catalano, ...
Frontiers in Cellular Neuroscience 8, 193, 2014
The chemokine CX3CL1 reduces migration and increases adhesion of neurons with mechanisms dependent on the β1 integrin subunit
C Lauro, M Catalano, F Trettel, F Mainiero, MT Ciotti, F Eusebi, C Limatola
The Journal of Immunology 177 (11), 7599-7606, 2006
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