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Lindsay Clark
Lindsay Clark
Postdoc researcher, Harvard Medical School
Bestätigte E-Mail-Adresse bei hms.harvard.edu
Titel
Zitiert von
Zitiert von
Jahr
High-resolution crystal structure of the human CB1 cannabinoid receptor
Z Shao, J Yin, K Chapman, M Grzemska, L Clark, J Wang, ...
Nature 540 (7634), 602-606, 2016
4142016
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors
J Yin, K Babaoglu, CA Brautigam, L Clark, Z Shao, TH Scheuermann, ...
Nature Structural & Molecular Biology 23 (4), 293-299, 2016
1382016
Ligand modulation of sidechain dynamics in a wild-type human GPCR
LD Clark, I Dikiy, K Chapman, KEJ Rödström, J Aramini, MV LeVine, ...
Elife 6, e28505, 2017
872017
Lipid dynamics and protein–lipid interactions in 2D crystals formed with the β-barrel integral membrane protein VDAC1
MT Eddy, TC Ong, L Clark, O Teijido, PCA van der Wel, R Garces, ...
Journal of the American Chemical Society 134 (14), 6375-6387, 2012
822012
Mechanism of membrane-curvature generation by ER-tubule shaping proteins
N Wang, LD Clark, Y Gao, MM Kozlov, T Shemesh, TA Rapoport
Nature communications 12 (1), 568, 2021
602021
Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris
L Clark, JA Zahm, R Ali, M Kukula, L Bian, SM Patrie, KH Gardner, ...
Journal of biomolecular NMR 62, 239-245, 2015
542015
Lipid bilayer-bound conformation of an integral membrane beta barrel protein by multidimensional MAS NMR
MT Eddy, Y Su, R Silvers, L Andreas, L Clark, G Wagner, G Pintacuda, ...
Journal of biomolecular NMR 61, 299-310, 2015
442015
Crystal structure of the human NK1 tachykinin receptor
J Yin, K Chapman, LD Clark, Z Shao, D Borek, Q Xu, J Wang, ...
Proceedings of the National Academy of Sciences 115 (52), 13264-13269, 2018
412018
On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies
L Clark, I Dikiy, DM Rosenbaum, KH Gardner
Journal of biomolecular NMR 71, 203-211, 2018
402018
Magic angle spinning nuclear magnetic resonance characterization of voltage-dependent anion channel gating in two-dimensional lipid crystalline bilayers
MT Eddy, L Andreas, O Teijido, Y Su, L Clark, SY Noskov, G Wagner, ...
Biochemistry 54 (4), 994-1005, 2015
402015
Direct demonstration that loop1 of Scap binds to loop7: a crucial event in cholesterol homeostasis
Y Zhang, KM Lee, LN Kinch, L Clark, NV Grishin, DM Rosenbaum, ...
Journal of Biological Chemistry 291 (24), 12888-12896, 2016
252016
Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing
DL Kober, A Radhakrishnan, JL Goldstein, MS Brown, LD Clark, X Bai, ...
Cell 184 (14), 3689-3701. e22, 2021
192021
Engineered disulfide bonds restore chaperone-like function of DJ-1 mutants linked to familial Parkinson’s disease
T Logan, L Clark, SS Ray
Biochemistry 49 (27), 5624-5633, 2010
122010
Improved strategy for isoleucine 1H/13C methyl labeling in Pichia pastoris
R Ali, LD Clark, JA Zahm, A Lemoff, K Ramesh, DM Rosenbaum, ...
Journal of biomolecular NMR 73, 687-697, 2019
112019
Isotopic labeling of eukaryotic membrane proteins for NMR studies of interactions and dynamics
I Dikiy, LD Clark, KH Gardner, DM Rosenbaum
Methods in enzymology 614, 37-65, 2019
92019
CA, Garces, R., Wagner, G., Rostovtseva, TK, and Griffin, RG (2012) Lipid Dynamics and Protein-Lipid Interactions in 2D Crystals Formed with the β-barrel Integral Membrane …
MT Eddy, TC Ong, L Clark, O Teijido, P Van Der Wel
J. Am. Chem. Soc 134, 6375-6387, 0
5
Structural Studies of Integral Membrane Proteins Involved in GPCR Signaling and Sterol Homeostasis
LD Clark
2018
Ligand Modulation of Sidechain Dynamics in a Wild-Type Human GPCR
LD Clark, I Dikiy, K Chapman, KE Rodstrom, J Aramini, MV LeVine, ...
Biophysical Journal 114 (3), 239a, 2018
2018
Magic angle NMR studies of bacterioshodopsin (bR) and the volage depndent anion channel (VDAC)
Q Ni, T Can, M Eddy, Y Su, R Silvers, L Andreas, L Clark, G Pintacuda, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017
2017
Erratum to: Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris
L Clark, JA Zahm, R Ali, M Kukula, L Bian, SM Patrie, KH Gardner, ...
Journal of biomolecular NMR 64, 267-267, 2016
2016
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