Curcumin is a potent DNA hypomethylation agent Z Liu, Z Xie, W Jones, RE Pavlovicz, S Liu, J Yu, P Li, J Lin, JR Fuchs, ... Bioorganic & medicinal chemistry letters 19 (3), 706-709, 2009 | 385 | 2009 |
Multi-targeted therapy of cancer by niclosamide: A new application for an old drug Y Li, PK Li, MJ Roberts, RC Arend, RS Samant, DJ Buchsbaum Cancer letters 349 (1), 8-14, 2014 | 367 | 2014 |
STAT3 is necessary for proliferation and survival in colon cancer–initiating cells L Lin, A Liu, Z Peng, HJ Lin, PK Li, C Li, J Lin Cancer research 71 (23), 7226-7237, 2011 | 335 | 2011 |
First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy M Sen, SM Thomas, S Kim, JI Yeh, RL Ferris, JT Johnson, U Duvvuri, ... Cancer discovery 2 (8), 694-705, 2012 | 318 | 2012 |
Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells L Lin, B Hutzen, M Zuo, S Ball, S Deangelis, E Foust, B Pandit, MA Ihnat, ... Cancer research 70 (6), 2445-2454, 2010 | 282 | 2010 |
A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells L Lin, B Hutzen, PK Li, S Ball, M Zuo, S DeAngelis, E Foust, M Sobo, ... Neoplasia 12 (1), 39-IN5, 2010 | 239 | 2010 |
JAK-STAT blockade inhibits tumor initiation and clonogenic recovery of prostate cancer stem-like cells P Kroon, PA Berry, MJ Stower, G Rodrigues, VM Mann, M Simms, ... Cancer research 73 (16), 5288-5298, 2013 | 207 | 2013 |
Sorafenib overcomes TRAIL resistance of hepatocellular carcinoma cells through the inhibition of STAT3 KF Chen, WT Tai, TH Liu, HP Huang, YC Lin, CW Shiau, PK Li, PJ Chen, ... Clinical cancer research 16 (21), 5189-5199, 2010 | 187 | 2010 |
Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells Y Liu, PK Li, C Li, J Lin Journal of Biological Chemistry 285 (35), 27429-27439, 2010 | 186 | 2010 |
Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030 L Lin, Y Liu, H Li, PK Li, J Fuchs, H Shibata, Y Iwabuchi, J Lin British journal of cancer 105 (2), 212-220, 2011 | 180 | 2011 |
Structure–activity relationship studies of curcumin analogues JR Fuchs, B Pandit, D Bhasin, JP Etter, N Regan, D Abdelhamid, C Li, ... Bioorganic & medicinal chemistry letters 19 (7), 2065-2069, 2009 | 176 | 2009 |
Modulation of DNA methylation by a sesquiterpene lactone parthenolide Z Liu, S Liu, Z Xie, RE Pavlovicz, J Wu, P Chen, J Aimiuwu, J Pang, ... Journal of Pharmacology and Experimental Therapeutics 329 (2), 505-514, 2009 | 165 | 2009 |
Glioma cell migration on three-dimensional nanofiber scaffolds is regulated by substrate topography and abolished by inhibition of STAT3 signaling PA Agudelo-Garcia, JK De Jesus, SP Williams, MO Nowicki, EA Chiocca, ... Neoplasia 13 (9), 831-IN22, 2011 | 156 | 2011 |
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells L Lin, S Deangelis, E Foust, J Fuchs, C Li, PK Li, EB Schwartz, ... Molecular cancer 9, 1-10, 2010 | 153 | 2010 |
Characterization of STAT3 activation and expression in canine and human osteosarcoma SL Fossey, AT Liao, JK McCleese, MD Bear, J Lin, PK Li, WC Kisseberth, ... BMC cancer 9, 1-15, 2009 | 151 | 2009 |
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity MA Bill, JR Fuchs, C Li, J Yui, C Bakan, DM Benson, EB Schwartz, ... Molecular cancer 9, 1-12, 2010 | 145 | 2010 |
Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury J Zhao, H Yu, Y Liu, SA Gibson, Z Yan, X Xu, A Gaggar, PK Li, C Li, S Wei, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (5 …, 2016 | 139 | 2016 |
Design, synthesis, and studies of small molecule STAT3 inhibitors D Bhasin, K Cisek, T Pandharkar, N Regan, C Li, B Pandit, J Lin, PK Li Bioorganic & medicinal chemistry letters 18 (1), 391-395, 2008 | 127 | 2008 |
Design and synthesis of Pfmrk inhibitors as potential antimalarial agents Z Xiao, NC Waters, CL Woodard, Z Li, PK Li Bioorganic & medicinal chemistry letters 11 (21), 2875-2878, 2001 | 124 | 2001 |
LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model B Fuh, M Sobo, L Cen, D Josiah, B Hutzen, K Cisek, D Bhasin, N Regan, ... British journal of cancer 100 (1), 106-112, 2009 | 118 | 2009 |