| T-cell quality in memory and protection: implications for vaccine design RA Seder, PA Darrah, M Roederer Nature Reviews Immunology 8 (4), 247-258, 2008 | 1793 | 2008 |
| Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major PA Darrah, DT Patel, PM De Luca, RWB Lindsay, DF Davey, BJ Flynn, ... Nature medicine 13 (7), 843-850, 2007 | 1604 | 2007 |
| Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells T Lindenstrøm, EM Agger, KS Korsholm, PA Darrah, C Aagaard, ... The Journal of Immunology 182 (12), 8047-8055, 2009 | 468 | 2009 |
| Prevention of tuberculosis in macaques after intravenous BCG immunization PA Darrah, JJ Zeppa, P Maiello, JA Hackney, MH Wadsworth, TK Hughes, ... Nature 577 (7788), 95-102, 2020 | 466 | 2020 |
| In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity GM Lynn, R Laga, PA Darrah, AS Ishizuka, AJ Balaci, AE Dulcey, ... Nature biotechnology 33 (11), 1201-1210, 2015 | 408 | 2015 |
| Role of the 85-Kilobase Plasmid and Plasmid-Encoded Virulence-Associated Protein A in Intracellular Survival and Virulence of Rhodococcus equi S Giguère, MK Hondalus, JA Yager, P Darrah, DM Mosser, JF Prescott Infection and immunity 67 (7), 3548-3557, 1999 | 255 | 1999 |
| Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets K Kastenmüller, U Wille-Reece, RWB Lindsay, LR Trager, PA Darrah, ... The Journal of clinical investigation 121 (5), 1782-1796, 2011 | 204 | 2011 |
| Cooperation between Reactive Oxygen and Nitrogen Intermediates in Killing of Rhodococcus equi by Activated Macrophages PA Darrah, MK Hondalus, Q Chen, H Ischiropoulos, DM Mosser Infection and immunity 68 (6), 3587-3593, 2000 | 178 | 2000 |
| IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform PA Darrah, ST Hegde, DT Patel, RWB Lindsay, L Chen, M Roederer, ... Journal of Experimental Medicine 207 (7), 1421-1433, 2010 | 127 | 2010 |
| Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and … KM Quinn, A Da Costa, A Yamamoto, D Berry, RWB Lindsay, PA Darrah, ... The Journal of Immunology 190 (6), 2720-2735, 2013 | 122 | 2013 |
| Dendritic Cells Are Responsible for the Capacity of CpG Oligodeoxynucleotides to Act as an Adjuvant for Protective Vaccine Immunity Against Leishmania major in … JA Shah, PA Darrah, DR Ambrozak, TN Turon, S Mendez, J Kirman, ... The Journal of experimental medicine 198 (2), 281-291, 2003 | 110 | 2003 |
| Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis … PA Darrah, DL Bolton, AA Lackner, D Kaushal, PP Aye, S Mehra, ... The Journal of Immunology 193 (4), 1799-1811, 2014 | 107 | 2014 |
| Prime-boost vaccination with HIV-1 Gag protein and cytosine phosphate guanosine oligodeoxynucleotide, followed by adenovirus, induces sustained and robust humoral and cellular … M Tritel, AM Stoddard, BJ Flynn, PA Darrah, C Wu, U Wille, JA Shah, ... The Journal of Immunology 171 (5), 2538-2547, 2003 | 100 | 2003 |
| Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling KM Quinn, DE Zak, A Costa, A Yamamoto, K Kastenmuller, BJ Hill, ... The Journal of clinical investigation 125 (3), 1129-1146, 2015 | 96 | 2015 |
| Pathogen-specific T cell polyfunctionality is a correlate of T cell efficacy and immune protection A Boyd, JR Almeida, PA Darrah, D Sauce, RA Seder, V Appay, ... PloS one 10 (6), e0128714, 2015 | 92 | 2015 |
| CD8+ T cell responses following replication-defective adenovirus serotype 5 immunization are dependent on CD11c+ dendritic cells but show redundancy in their requirement of TLR … RWB Lindsay, PA Darrah, KM Quinn, U Wille-Reece, LM Mattei, A Iwasaki, ... The Journal of Immunology 185 (3), 1513-1521, 2010 | 88 | 2010 |
| Innate immune responses to Rhodococcus equi PA Darrah, MCG Monaco, S Jain, MK Hondalus, DT Golenbock, ... The Journal of Immunology 173 (3), 1914-1924, 2004 | 70 | 2004 |
| Robust IgM responses following intravenous vaccination with Bacille Calmette–Guérin associate with prevention of Mycobacterium tuberculosis infection in … EB Irvine, A O’Neil, PA Darrah, S Shin, A Choudhary, W Li, W Honnen, ... Nature immunology 22 (12), 1515-1523, 2021 | 58 | 2021 |
| SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination NR Klatt, CL Vinton, RM Lynch, LA Canary, J Ho, PA Darrah, JD Estes, ... Blood, The Journal of the American Society of Hematology 118 (22), 5803-5812, 2011 | 58 | 2011 |
| Monocytes acquire the ability to prime tissue-resident T cells via IL-10-mediated TGF-β release EA Thompson, PA Darrah, KE Foulds, E Hoffer, A Caffrey-Carr, ... Cell reports 28 (5), 1127-1135. e4, 2019 | 57 | 2019 |
