| Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy RL Vidal, A Figueroa, FA Court, P Thielen, C Molina, C Wirth, B Caballero, ... Human molecular genetics 21 (10), 2245-2262, 2012 | 263 | 2012 |
| Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1 P Valdés, G Mercado, RL Vidal, C Molina, G Parsons, FA Court, ... Proceedings of the National Academy of Sciences 111 (18), 6804-6809, 2014 | 219 | 2014 |
| Outside in: Unraveling the Role of Neuroinflammation in the Progression of Parkinson's Disease P Troncoso-Escudero, A Parra, M Nassif, RL Vidal Frontiers in neurology 9, 413854, 2018 | 181 | 2018 |
| Targeting autophagy in neurodegenerative diseases RL Vidal, S Matus, L Bargsted, C Hetz Trends in pharmacological sciences 35 (11), 583-591, 2014 | 177 | 2014 |
| Regulation of memory formation by the transcription factor XBP1 G Martínez, RL Vidal, P Mardones, FG Serrano, AO Ardiles, C Wirth, ... Cell reports 14 (6), 1382-1394, 2016 | 172 | 2016 |
| Converging pathways in the occurrence of endoplasmic reticulum (ER) stress in Huntington's disease R Vidal, B Caballero, A Couve, C Hetz Current molecular medicine 11 (1), 1-12, 2011 | 142 | 2011 |
| ALS‐linked protein disulfide isomerase variants cause motor dysfunction U Woehlbier, A Colombo, MJ Saaranen, V Pérez, J Ojeda, FJ Bustos, ... The EMBO journal 35 (8), 845-865, 2016 | 118 | 2016 |
| Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis M Nassif, V Valenzuela, D Rojas-Rivera, R Vidal, S Matus, K Castillo, ... Autophagy 10 (7), 1256-1271, 2014 | 118 | 2014 |
| IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A H Urra, DR Henriquez, J Cánovas, D Villarroel-Campos, ... Nature cell biology 20 (8), 942-953, 2018 | 116 | 2018 |
| A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington’s disease in mice AI Acuña, M Esparza, C Kramm, FA Beltrán, AV Parra, C Cepeda, ... Nature communications 4 (1), 2917, 2013 | 110 | 2013 |
| AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington’s disease A Zuleta, RL Vidal, D Armentano, G Parsons, C Hetz Biochemical and biophysical research communications 420 (3), 558-563, 2012 | 99 | 2012 |
| Court FA, Martinez A, Galleguillos D, Armentano D, Schneider BL, Hetz C (2014) Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1 P Valdes, G Mercado, RL Vidal, C Molina, G Parsons Proc Natl Acad Sci USA 111 (18), 6804-6809, 0 | 78 | |
| Targeting the unfolded protein response for disease intervention A Rivas, RL Vidal, C Hetz Expert opinion on therapeutic targets 19 (9), 1203-1218, 2015 | 75 | 2015 |
| Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease RL Vidal, C Hetz Autophagy 8 (6), 970-972, 2012 | 60 | 2012 |
| Role of the unfolded protein response in organ physiology: lessons from mouse models VH Cornejo, P Pihán, RL Vidal, C Hetz IUBMB life 65 (12), 962-975, 2013 | 59 | 2013 |
| Court FA, Thielen P, Molina C, Wirth C, Caballero B, Kiffin R, Segura-Aguilar J, Cuervo AM, Glimcher LH, Hetz C (2012) Targeting the UPR transcription factor XBP1 protects … RL Vidal, A Figueroa Hum Mol Genet 21 (10), 2245-2262, 0 | 55 | |
| Functional role of the disulfide isomerase ERp57 in axonal regeneration V Castillo, M Oñate, U Woehlbier, P Rozas, C Andreu, D Medinas, ... PloS one 10 (9), e0136620, 2015 | 52 | 2015 |
| Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates P García-Huerta, P Troncoso-Escudero, D Wu, A Thiruvalluvan, ... Acta neuropathologica 140, 737-764, 2020 | 51 | 2020 |
| The intersection between growth factors, autophagy and ER stress: A new target to treat neurodegenerative diseases? P Garcia-Huerta, P Troncoso-Escudero, C Jerez, C Hetz, RL Vidal Brain research 1649, 173-180, 2016 | 51 | 2016 |
| Dendritic assembly of heteromeric γ-aminobutyric acid type B receptor subunits in hippocampal neurons OA Ramírez, RL Vidal, JA Tello, KJ Vargas, S Kindler, S Härtel, A Couve Journal of biological chemistry 284 (19), 13077-13085, 2009 | 49 | 2009 |
