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Nicholas Gascoigne
Nicholas Gascoigne
Professor, Department of Microbiology, Yong Loo Lin School of Medicine, National University of
Bestätigte E-Mail-Adresse bei nus.edu.sg
Titel
Zitiert von
Zitiert von
Jahr
T-cell-receptor affinity and thymocyte positive selection
SM Alam, PJ Travers, JL Wung, W Nasholds, S Redpath, SC Jameson, ...
Nature 381 (6583), 616-620, 1996
8351996
Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor
J Kaye, ML Hsu, ME Sauron, SC Jameson, NRJ Gascoigne, SM Hedrick
Nature 341 (6244), 746-749, 1989
7791989
Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
MA Daniels, E Teixeiro, J Gill, B Hausmann, D Roubaty, K Holmberg, ...
Nature 444 (7120), 724-729, 2006
7052006
Somatic recombination in a murine T-cell receptor gene
Y Chien, NRJ Gascoigne, J Kavaler, NE Lee, MM Davis
Nature 309 (5966), 322-326, 1984
5851984
Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes
NRJ Gascoigne, Y Chien, DM Becker, J Kavaler, MM Davis
Nature 310 (5976), 387-391, 1984
4751984
Photobleaching-corrected FRET efficiency imaging of live cells
T Zal, NRJ Gascoigne
Biophysical journal 86 (6), 3923-3939, 2004
4482004
Hijacking and exploitation of IL-10 by intracellular pathogens
S Redpath, P Ghazal, NRJ Gascoigne
Trends in microbiology 9 (2), 86-92, 2001
4032001
The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model
C Rosette, G Werlen, MA Daniels, PO Holman, SM Alam, PJ Travers, ...
Immunity 15 (1), 59-70, 2001
3042001
Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands
SM Alam, GM Davies, CM Lin, T Zal, W Nasholds, SC Jameson, ...
Immunity 10 (2), 227-237, 1999
2791999
Murine cytomegalovirus infection down-regulates MHC class II expression on macrophages by induction of IL-10
S Redpath, A Angulo, NRJ Gascoigne, P Ghazal
The Journal of Immunology 162 (11), 6701-6707, 1999
2131999
Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection
T Nabekura, M Kanaya, A Shibuya, G Fu, NRJ Gascoigne, LL Lanier
Immunity 40 (2), 225-234, 2014
1992014
Control of MHC restriction by TCR Vα CDR1 and CDR2
BC Sim, L Zerva, MI Greene, NRJ Gascoigne
Science 273 (5277), 963-966, 1996
1901996
CD28 plays a critical role in the segregation of PKCθ within the immunologic synapse
J Huang, PF Lo, T Żal, NRJ Gascoigne, BA Smith, SD Levin, HM Grey
Proceedings of the National Academy of Sciences 99 (14), 9369-9373, 2002
1882002
TCR affinity and negative regulation limit autoimmunity
MA Gronski, JM Boulter, D Moskophidis, LT Nguyen, K Holmberg, ...
Nature medicine 10 (11), 1234-1239, 2004
1802004
Monoclonal antibody-superantigen fusion proteins: tumor-specific agents for T-cell-based tumor therapy.
M Dohlsten, L Abrahmsen, P Björk, PA Lando, G Hedlund, G Forsberg, ...
Proceedings of the National Academy of Sciences 91 (19), 8945-8949, 1994
1781994
Variability and repertoire size of T-cell receptor Vα gene segments
DM Becker, P Patten, Y Chien, T Yokota, Z Eshhar, M Giedlin, ...
Nature 317 (6036), 430-434, 1985
1761985
Altered peptide ligands induce delayed CD8-T cell receptor interaction—a role for CD8 in distinguishing antigen quality
PP Yachi, J Ampudia, T Zal, NRJ Gascoigne
Immunity 25 (2), 203-211, 2006
1752006
TCR signal strength and T cell development
NRJ Gascoigne, V Rybakin, O Acuto, J Brzostek
Annual review of cell and developmental biology 32, 327-348, 2016
1702016
Nonstimulatory peptides contribute to antigen-induced CD8–T cell receptor interaction at the immunological synapse
PP Yachi, J Ampudia, NRJ Gascoigne, T Zal
Nature immunology 6 (8), 785-792, 2005
1642005
The Vα14 NKT cell TCR exhibits high-affinity binding to a glycolipid/CD1d complex
S Sidobre, OV Naidenko, BC Sim, NRJ Gascoigne, KC Garcia, ...
The Journal of Immunology 169 (3), 1340-1348, 2002
1642002
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