| The mechanisms of pharmacokinetic food-drug interactions–A perspective from the UNGAP group M Koziolek, S Alcaro, P Augustijns, AW Basit, M Grimm, B Hens, CL Hoad, ... European Journal of Pharmaceutical Sciences 134, 31-59, 2019 | 300 | 2019 |
| Favipiravir at high doses has potent antiviral activity in SARS-CoV-2− infected hamsters, whereas hydroxychloroquine lacks activity SJF Kaptein, S Jacobs, L Langendries, L Seldeslachts, S Ter Horst, ... Proceedings of the National Academy of Sciences 117 (43), 26955-26965, 2020 | 278 | 2020 |
| A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption P Augustijns, B Wuyts, B Hens, P Annaert, J Butler, J Brouwers European Journal of Pharmaceutical Sciences 57, 322-332, 2014 | 202 | 2014 |
| Supersaturation and precipitation of posaconazole upon entry in the upper small intestine in humans B Hens, J Brouwers, M Corsetti, P Augustijns Journal of pharmaceutical sciences 105 (9), 2677-2684, 2016 | 119 | 2016 |
| In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration J Butler, B Hens, M Vertzoni, J Brouwers, P Berben, J Dressman, ... European Journal of Pharmaceutics and Biopharmaceutics 136, 70-83, 2019 | 117 | 2019 |
| Low Buffer Capacity and Alternating Motility along the Human Gastrointestinal Tract: Implications for in Vivo Dissolution and Absorption of Ionizable Drugs B Hens, Y Tsume, M Bermejo, P Paixao, MJ Koenigsknecht, JR Baker, ... Molecular pharmaceutics 14 (12), 4281-4294, 2017 | 115 | 2017 |
| Exploring gastrointestinal variables affecting drug and formulation behavior: methodologies, challenges and opportunities B Hens, M Corsetti, R Spiller, L Marciani, T Vanuytsel, J Tack, A Talattof, ... International Journal of Pharmaceutics 519 (1-2), 79-97, 2017 | 106 | 2017 |
| Gastrointestinal behavior of nano-and microsized fenofibrate: in vivo evaluation in man and in vitro simulation by assessment of the permeation potential B Hens, J Brouwers, M Corsetti, P Augustijns European Journal of Pharmaceutical Sciences 77, 40-47, 2015 | 96 | 2015 |
| Supersaturation in human gastric fluids J Bevernage, B Hens, J Brouwers, J Tack, P Annaert, P Augustijns European journal of pharmaceutics and biopharmaceutics 81 (1), 184-189, 2012 | 77 | 2012 |
| Gastrointestinal transfer: in vivo evaluation and implementation in in vitro and in silico predictive tools B Hens, J Brouwers, B Anneveld, M Corsetti, M Symillides, M Vertzoni, ... European journal of pharmaceutical sciences 63, 233-242, 2014 | 74 | 2014 |
| In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole B Hens, SM Pathak, A Mitra, N Patel, B Liu, S Patel, M Jamei, J Brouwers, ... Molecular pharmaceutics 14 (12), 4321-4333, 2017 | 71 | 2017 |
| Persistent threats by persistent pollutants: chemical nature, concerns and future policy regarding PCBs—what are we heading for? B Hens, L Hens Toxics 6 (1), 1, 2017 | 67 | 2017 |
| A mechanistic physiologically-based biopharmaceutics modeling (PBBM) approach to assess the in vivo performance of an orally administered drug product: from IVIVC to IVIVP M Bermejo, B Hens, J Dickens, D Mudie, P Paixão, Y Tsume, K Shedden, ... Pharmaceutics 12 (1), 74, 2020 | 54 | 2020 |
| Evaluation and optimized selection of supersaturating drug delivery systems of posaconazole (BCS class 2b) in the gastrointestinal simulator (GIS): An in vitro-in silico-in … B Hens, M Bermejo, Y Tsume, I Gonzalez-Alvarez, H Ruan, K Matsui, ... European Journal of Pharmaceutical Sciences 115, 258-269, 2018 | 53 | 2018 |
| Gastrointestinal and systemic monitoring of posaconazole in humans after fasted and fed state administration of a solid dispersion B Hens, M Corsetti, J Brouwers, P Augustijns Journal of Pharmaceutical Sciences 105 (9), 2904-2912, 2016 | 52 | 2016 |
| Formulation predictive dissolution (fPD) testing to advance oral drug product development: An introduction to the US FDA funded ‘21st Century BA/BE’project B Hens, PD Sinko, N Job, M Dean, J Al-Gousous, N Salehi, RM Ziff, ... International journal of pharmaceutics 548 (1), 120-127, 2018 | 48 | 2018 |
| Bile salt micelles and phospholipid vesicles present in simulated and human intestinal fluids: structural analysis by flow field–flow fractionation/multiangle laser light … PA Elvang, AH Hinna, J Brouwers, B Hens, P Augustijns, M Brandl Journal of Pharmaceutical Sciences 105 (9), 2832-2839, 2016 | 45 | 2016 |
| Application of a dynamic fluid and pH model to simulate intraluminal and systemic concentrations of a weak base in GastroPlus™ B Hens, MB Bolger Journal of pharmaceutical sciences 108 (1), 305-315, 2019 | 37 | 2019 |
| Mass Transport Analysis of the Enhanced Buffer Capacity of the Bicarbonate–CO2 Buffer in a Phase-Heterogenous System: Physiological and Pharmaceutical … J Al-Gousous, KX Sun, DP McNamara, B Hens, N Salehi, P Langguth, ... Molecular pharmaceutics 15 (11), 5291-5301, 2018 | 31 | 2018 |
| Antiviral treatment of SARS-CoV-2-infected hamsters reveals a weak effect of favipiravir and a complete lack of effect for hydroxychloroquine SJF Kaptein, S Jacobs, L Langendries, L Seldeslachts, S ter Horst, ... BioRxiv, 2020.06. 19.159053, 2020 | 30 | 2020 |
