Amyloid beta deregulates astroglial mGluR5‐mediated calcium signaling via calcineurin and Nf‐kB D Lim, A Iyer, V Ronco, AA Grolla, PL Canonico, E Aronica, AA Genazzani Glia 61 (7), 1134-1145, 2013 | 161 | 2013 |
WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway G Fakhfouri, A Ahmadiani, R Rahimian, AA Grolla, F Moradi, A Haeri Neuropharmacology 63 (4), 653-666, 2012 | 129 | 2012 |
Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine AA Grolla, C Travelli, AA Genazzani, JK Sethi British journal of pharmacology 173 (14), 2182-2194, 2016 | 124 | 2016 |
Characterization of NAD uptake in mammalian cells RA Billington, C Travelli, E Ercolano, U Galli, CB Roman, AA Grolla, ... Journal of Biological Chemistry 283 (10), 6367-6374, 2008 | 117 | 2008 |
Amyloid-β and Alzheimer’s disease type pathology differentially affects the calcium signalling toolkit in astrocytes from different brain regions AA Grolla, JA Sim, D Lim, JJ Rodriguez, AA Genazzani, A Verkhratsky Cell death & disease 4 (5), e623-e623, 2013 | 105 | 2013 |
Recent advances in NAMPT inhibitors: a novel immunotherapic strategy U Galli, G Colombo, C Travelli, GC Tron, AA Genazzani, AA Grolla Frontiers in pharmacology 11, 531540, 2020 | 98 | 2020 |
Aβ leads to Ca2+ signaling alterations and transcriptional changes in glial cells AA Grolla, G Fakhfouri, G Balzaretti, E Marcello, F Gardoni, PL Canonico, ... Neurobiology of aging 34 (2), 511-522, 2013 | 95 | 2013 |
Differential deregulation of astrocytic calcium signalling by amyloid-β, TNFα, IL-1β and LPS V Ronco, AA Grolla, TN Glasnov, PL Canonico, A Verkhratsky, ... Cell Calcium 55 (4), 219-229, 2014 | 87 | 2014 |
Glial calcium signalling in Alzheimer’s disease D Lim, V Ronco, AA Grolla, A Verkhratsky, AA Genazzani Reviews of Physiology, Biochemistry and Pharmacology, Vol. 167, 45-65, 2014 | 81 | 2014 |
Differentiation of adipose-derived stem cells into Schwann cell phenotype induces expression of P2X receptors that control cell death A Faroni, SW Rothwell, AA Grolla, G Terenghi, V Magnaghi, A Verkhratsky Cell death & disease 4 (7), e743-e743, 2013 | 68 | 2013 |
Nicotinamide phosphoribosyltransferase acts as a metabolic gate for mobilization of myeloid-derived suppressor cells C Travelli, FM Consonni, S Sangaletti, M Storto, S Morlacchi, AA Grolla, ... Cancer research 79 (8), 1938-1951, 2019 | 67 | 2019 |
Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is a tumoural cytokine released from melanoma AA Grolla, S Torretta, I Gnemmi, A Amoruso, G Orsomando, M Gatti, ... Pigment cell & melanoma research 28 (6), 718-729, 2015 | 63 | 2015 |
Identification of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors endowed with antiproliferative and antiinflammatory activity C Travelli, S Aprile, R Rahimian, AA Grolla, F Rogati, M Bertolotti, ... Journal of medicinal chemistry 60 (5), 1768-1792, 2017 | 56 | 2017 |
Synthesis, biological evaluation, and molecular docking of Ugi products containing a zinc-chelating moiety as novel inhibitors of histone deacetylases AA Grolla, V Podesta, MG Chini, S Di Micco, A Vallario, AA Genazzani, ... Journal of medicinal chemistry 52 (9), 2776-2785, 2009 | 44 | 2009 |
Neutralization of extracellular NAMPT (nicotinamide phosphoribosyltransferase) ameliorates experimental murine colitis G Colombo, N Clemente, A Zito, C Bracci, FS Colombo, S Sangaletti, ... Journal of Molecular Medicine 98, 595-612, 2020 | 36 | 2020 |
Synthesis, molecular docking and biological evaluation as HDAC inhibitors of cyclopeptide mimetics by a tandem three-component reaction and intramolecular [3+ 2] cycloaddition T Pirali, V Faccio, R Mossetti, AA Grolla, S Di Micco, G Bifulco, ... Molecular diversity 14, 109-121, 2010 | 34 | 2010 |
Triazole-curcuminoids: a new class of derivatives for ‘tuning’curcumin bioactivities? D Caprioglio, S Torretta, M Ferrari, C Travelli, AA Grolla, F Condorelli, ... Bioorganic & Medicinal Chemistry 24 (2), 140-152, 2016 | 31 | 2016 |
OXER1 and RACK1-associated pathway: A promising drug target for breast cancer progression M Masi, E Garattini, M Bolis, D Di Marino, L Maraccani, E Morelli, ... Oncogenesis 9 (12), 105, 2020 | 29 | 2020 |
A nicotinamide phosphoribosyltransferase–GAPDH interaction sustains the stress-induced NMN/NAD+ salvage pathway in the nucleus AA Grolla, R Miggiano, D Di Marino, M Bianchi, A Gori, G Orsomando, ... Journal of Biological Chemistry 295 (11), 3635-3651, 2020 | 26 | 2020 |
Synthesis and degradation of adenosine 5′-tetraphosphate by nicotinamide and nicotinate phosphoribosyltransferases A Amici, AA Grolla, E Del Grosso, R Bellini, M Bianchi, C Travelli, ... Cell Chemical Biology 24 (5), 553-564. e4, 2017 | 20 | 2017 |