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Thaddeus S. Stappenbeck
Thaddeus S. Stappenbeck
Bestätigte E-Mail-Adresse bei ccf.org
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A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility
MS Desai, AM Seekatz, NM Koropatkin, N Kamada, CA Hickey, M Wolter, ...
Cell 167 (5), 1339-1353. e21, 2016
24662016
Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases
J Lloyd-Price, C Arze, AN Ananthakrishnan, M Schirmer, J Avila-Pacheco, ...
Nature 569 (7758), 655-662, 2019
20442019
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
K Cadwell, JY Liu, SL Brown, H Miyoshi, J Loh, JK Lennerz, C Kishi, W Kc, ...
Nature 456 (7219), 259-263, 2008
17622008
Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells
TS Stappenbeck, LV Hooper, JI Gordon
Proceedings of the National Academy of Sciences 99 (24), 15451-15455, 2002
14072002
Disease-specific alterations in the enteric virome in inflammatory bowel disease
JM Norman, SA Handley, MT Baldridge, L Droit, CY Liu, BC Keller, ...
Cell 160 (3), 447-460, 2015
12662015
Peripheral education of the immune system by colonic commensal microbiota
SK Lathrop, SM Bloom, SM Rao, K Nutsch, CW Lio, N Santacruz, ...
Nature 478 (7368), 250-254, 2011
12132011
Angiogenins: a new class of microbicidal proteins involved in innate immunity
LV Hooper, TS Stappenbeck, CV Hong, JI Gordon
Nature immunology 4 (3), 269-273, 2003
11882003
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
K Cadwell, KK Patel, NS Maloney, TC Liu, ACY Ng, CE Storer, RD Head, ...
Cell 141 (7), 1135-1145, 2010
9942010
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8α+ conventional dendritic cells
BT Edelson, W KC, R Juang, M Kohyama, LA Benoit, PA Klekotka, ...
Journal of Experimental Medicine 207 (4), 823-836, 2010
8532010
Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury
SL Pull, JM Doherty, JC Mills, JI Gordon, TS Stappenbeck
Proceedings of the National Academy of Sciences 102 (1), 99-104, 2005
7422005
In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture
H Miyoshi, TS Stappenbeck
Nature protocols 8 (12), 2471-2482, 2013
6972013
The colonic crypt protects stem cells from microbiota-derived metabolites
GE Kaiko, SH Ryu, OI Koues, PL Collins, L Solnica-Krezel, EJ Pearce, ...
Cell 165 (7), 1708-1720, 2016
6732016
Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential
DL Worthley, M Churchill, JT Compton, Y Tailor, M Rao, Y Si, D Levin, ...
Cell 160 (1), 269-284, 2015
6452015
Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease
SM Bloom, VN Bijanki, GM Nava, L Sun, NP Malvin, DL Donermeyer, ...
Cell host & microbe 9 (5), 390-403, 2011
5182011
Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays
KL VanDussen, JM Marinshaw, N Shaikh, H Miyoshi, C Moon, PI Tarr, ...
Gut 64 (6), 911-920, 2015
4932015
Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury
H Miyoshi, R Ajima, CT Luo, TP Yamaguchi, TS Stappenbeck
Science 338 (6103), 108-113, 2012
4912012
The microbial metabolite desaminotyrosine protects from influenza through type I interferon
AL Steed, GP Christophi, GE Kaiko, L Sun, VM Goodwin, U Jain, ...
Science 357 (6350), 498-502, 2017
4642017
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens
AT Satpathy, CG Briseño, JS Lee, D Ng, NA Manieri, W Kc, X Wu, ...
Nature immunology 14 (9), 937-948, 2013
4542013
The role of stromal stem cells in tissue regeneration and wound repair
TS Stappenbeck, H Miyoshi
Science 324 (5935), 1666-1669, 2009
4232009
Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
KG Lassen, P Kuballa, KL Conway, KK Patel, CE Becker, JM Peloquin, ...
Proceedings of the National Academy of Sciences 111 (21), 7741-7746, 2014
4052014
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