Follow
Xiao Yang
Xiao Yang
Verified email at cuhk.edu.hk
Title
Cited by
Cited by
Year
Bacterial transcription as a target for antibacterial drug development
C Ma, X Yang, PJ Lewis
Microbiology and Molecular Biology Reviews 80 (1), 139-160, 2016
1462016
The structure of bacterial RNA polymerase in complex with the essential transcription elongation factor NusA
X Yang, S Molimau, GP Doherty, EB Johnston, J Marles‐Wright, ...
EMBO reports 10 (9), 997-1002, 2009
732009
Inhibitors of bacterial transcription initiation complex formation
C Ma, X Yang, H Kandemir, M Mielczarek, EB Johnston, R Griffith, ...
ACS Chemical Biology 8 (9), 1972-1980, 2013
672013
ε, a new subunit of RNA polymerase found in gram-positive bacteria
AN Keller, X Yang, J Wiedermannová, O Delumeau, L Krásný, PJ Lewis
Journal of bacteriology 196 (20), 3622-3632, 2014
542014
Overproduction and purification of recombinant Bacillus subtilis RNA polymerase
X Yang, PJ Lewis
Protein expression and purification 59 (1), 86-93, 2008
472008
Design, synthesis, nitric oxide release and antibacterial evaluation of novel nitrated ocotillol-type derivatives
Y Bi, X Yang, T Zhang, Z Liu, X Zhang, J Lu, K Cheng, J Xu, H Wang, G Lv, ...
European Journal of Medicinal Chemistry 101, 71-80, 2015
432015
Synthesis and biological activity of novel mono-indole and mono-benzofuran inhibitors of bacterial transcription initiation complex formation
M Mielczarek, RV Thomas, C Ma, H Kandemir, X Yang, M Bhadbhade, ...
Bioorganic & Medicinal Chemistry 23 (8), 1763-1775, 2015
412015
Synthesis and biological activity of novel bis-indole inhibitors of bacterial transcription initiation complex formation
M Mielczarek, RV Devakaram, C Ma, X Yang, H Kandemir, B Purwono, ...
Organic & biomolecular chemistry 12 (18), 2882-2894, 2014
412014
RNA polymerase-induced remodelling of NusA produces a pause enhancement complex
C Ma, M Mobli, X Yang, AN Keller, GF King, PJ Lewis
Nucleic acids research 43 (5), 2829-2840, 2015
362015
Bacterial transcription inhibitor of RNA polymerase holoenzyme formation by structure-based drug design: from in silico screening to validation
C Ma, X Yang, PJ Lewis
ACS infectious diseases 2 (1), 39-46, 2016
322016
Selective enrichment and identification of cross-linked peptides to study 3-D structures of protein complexes by mass spectrometry
H Buncherd, MA Nessen, N Nouse, SK Stelder, W Roseboom, HL Dekker, ...
Journal of proteomics 75 (7), 2205-2215, 2012
322012
Temporal and spatial expression of hexose transporters in developing tomato (Lycopersicon esculentum) fruit
SJ Dibley, ML Gear, X Yang, EG Rosche, CE Offler, DW McCurdy, ...
Functional Plant Biology 32 (9), 777-785, 2005
302005
Blood-glucose-lowering effect of coptidis rhizoma extracts from different origins via gut microbiota modulation in db/db mice
Y Lyu, SCK Cheung, PC Shaw, PKS Chan, APS Kong, Z Zuo
Frontiers in Pharmacology 12, 684358, 2021
292021
Synthesis and antibacterial evaluation of novel 3-substituted ocotillol-type derivatives as leads
Y Bi, XX Liu, HY Zhang, X Yang, ZY Liu, J Lu, PJ Lewis, CZ Wang, JY Xu, ...
Molecules 22 (4), 590, 2017
292017
Novel N-Substituted oseltamivir derivatives as potent influenza neuraminidase inhibitors: Design, synthesis, biological evaluation, ADME prediction and molecular docking studies
J Ye, X Yang, M Xu, PK Chan, C Ma
European journal of medicinal chemistry 182, 111635, 2019
262019
Systematic review of human gut resistome studies revealed variable definitions and approaches
J Ho, YK Yeoh, N Barua, Z Chen, G Lui, SH Wong, X Yang, MCW Chan, ...
Gut Microbes 12 (1), 1700755, 2020
242020
The interaction between RNA polymerase and the elongation factor NusA
X Yang, PJ Lewis
RNA biology 7 (3), 272-275, 2010
242010
Discovery of antibacterials that inhibit bacterial RNA polymerase interactions with sigma factors
J Ye, AJ Chu, R Harper, ST Chan, TL Shek, Y Zhang, M Ip, M Sambir, ...
Journal of medicinal chemistry 63 (14), 7695-7720, 2020
212020
Nusbiarylins, a new class of antimicrobial agents: Rational design of bacterial transcription inhibitors targeting the interaction between the NusB and NusE proteins
Y Qiu, ST Chan, L Lin, TL Shek, TF Tsang, Y Zhang, M Ip, PK Chan, ...
Bioorganic Chemistry 92, 103203, 2019
212019
Identification of inhibitors of bacterial RNA polymerase
X Yang, C Ma, PJ Lewis
Methods 86, 45-50, 2015
212015
The system can't perform the operation now. Try again later.
Articles 1–20