Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism V Tropepe, S Hitoshi, C Sirard, TW Mak, J Rossant, D Van Der Kooy Neuron 30 (1), 65-78, 2001 | 949 | 2001 |
Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells S Hitoshi, T Alexson, V Tropepe, D Donoviel, AJ Elia, JS Nye, RA Conlon, ... Genes & development 16 (7), 846-858, 2002 | 847 | 2002 |
Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain S Hitoshi, V Tropepe, M Ekker, D van der Kooy Oxford University Press for The Company of Biologists Limited 129 (1), 233-244, 2002 | 284 | 2002 |
Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling S Hitoshi, RM Seaberg, C Koscik, T Alexson, S Kusunoki, I Kanazawa, ... Genes & development 18 (15), 1806-1811, 2004 | 245 | 2004 |
Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs M Ema, D Mori, H Niwa, Y Hasegawa, Y Yamanaka, S Hitoshi, J Mimura, ... Cell stem cell 3 (5), 555-567, 2008 | 230 | 2008 |
Experimental sensory neuropathy induced by sensitization with ganglioside GD1b S Kusunoki, J Shimizu, A Chiba, Y Ugawa, S Hitoshi, I Kanazawa Annals of neurology 39 (4), 424-431, 1996 | 224 | 1996 |
Novel missense variants of prion protein in Creutzfeldt-Jakob disease or Gerstmann-Sträussler syndrome T Kitamoto, M Ohta, K Dohura, S Hitoshi, Y Terao, J Tateishi Biochemical and biophysical research communications 191 (2), 709-714, 1993 | 212 | 1993 |
Mid-brain pathology of Wilson's disease: MRI analysis of three cases. S Hitoshi, M Iwata, K Yoshikawa Journal of Neurology, Neurosurgery & Psychiatry 54 (7), 624-626, 1991 | 175 | 1991 |
Notch signaling is required to maintain all neural stem cell populations–irrespective of spatial or temporal niche TO Alexson, S Hitoshi, BL Coles, A Bernstein, D van der Kooy Developmental neuroscience 28 (1-2), 34-48, 2006 | 163 | 2006 |
Antidepressant drugs reverse the loss of adult neural stem cells following chronic stress S Hitoshi, N Maruta, M Higashi, A Kumar, N Kato, K Ikenaka Journal of neuroscience research 85 (16), 3574-3585, 2007 | 149 | 2007 |
Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival T Wada, JJ Haigh, M Ema, S Hitoshi, R Chaddah, J Rossant, A Nagy, ... Journal of Neuroscience 26 (25), 6803-6812, 2006 | 143 | 2006 |
Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells N Sasaki, K Okishio, K Ui-Tei, K Saigo, A Kinoshita-Toyoda, H Toyoda, ... Journal of biological chemistry 283 (6), 3594-3606, 2008 | 133 | 2008 |
GM1b is a new member of antigen for serum antibody in Guillain-Barré syndrome S Kusunoki, M Iwamori, A Chiba, S Hitoshi, M Arita, I Kanazawa Neurology 47 (1), 237-242, 1996 | 120 | 1996 |
Anti‐Gal‐C antibody in autoimmune neuropathies subsequent to mycoplasma infection S Kusunoki, A Chiba, S Hitoshi, H Takizawa, I Kanazawa Muscle & Nerve: Official Journal of the American Association of …, 1995 | 113 | 1995 |
Mechanisms for interferon-α-induced depression and neural stem cell dysfunction LS Zheng, S Hitoshi, N Kaneko, K Takao, T Miyakawa, Y Tanaka, H Xia, ... Stem cell reports 3 (1), 73-84, 2014 | 90 | 2014 |
Neuron-specific gene transfer through retrograde transport of lentiviral vector pseudotyped with a novel type of fusion envelope glycoprotein S Kato, M Kuramochi, K Takasumi, K Kobayashi, K Inoue, D Takahara, ... Human gene therapy 22 (12), 1511-1523, 2011 | 86 | 2011 |
Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells S Hitoshi, Y Ishino, A Kumar, S Jasmine, KF Tanaka, T Kondo, S Kato, ... Nature neuroscience 14 (8), 957-964, 2011 | 82 | 2011 |
Monospecific anti‐GD1b IgG is required to induce rabbit ataxic neuropathy S Kusunoki, S Hitoshi, KI Kaida, M Arita, I Kanazawa Annals of Neurology: Official Journal of the American Neurological …, 1999 | 79 | 1999 |
Developmental changes in the expression of glycogenes and the content of N-glycans in the mouse cerebral cortex A Ishii, T Ikeda, S Hitoshi, I Fujimoto, T Torii, K Sakuma, S Nakakita, ... Glycobiology 17 (3), 261-276, 2007 | 73 | 2007 |
Molecular cloning and expression of two types of rabbit β-galactoside α1, 2-fucosyltransferase S Hitoshi, S Kusunoki, I Kanazawa, S Tsuji Journal of Biological Chemistry 270 (15), 8844-8850, 1995 | 73 | 1995 |