Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms C Buettner, ED Muse, A Cheng, L Chen, T Scherer, A Pocai, K Su, ... Nature medicine 14 (6), 667-675, 2008 | 403 | 2008 |
De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health L Eissing, T Scherer, K Tödter, U Knippschild, JW Greve, WA Buurman, ... Nature communications 4 (1), 1528, 2013 | 358 | 2013 |
Brain insulin controls adipose tissue lipolysis and lipogenesis T Scherer, J O'Hare, K Diggs-Andrews, M Schweiger, B Cheng, ... Cell metabolism 13 (2), 183-194, 2011 | 320 | 2011 |
Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice J Liu, L Zhou, K Xiong, G Godlewski, B Mukhopadhyay, J Tam, S Yin, ... Gastroenterology 142 (5), 1218-1228. e1, 2012 | 189 | 2012 |
Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism AC Shin, M Fasshauer, N Filatova, LA Grundell, E Zielinski, JY Zhou, ... Cell metabolism 20 (5), 898-909, 2014 | 167 | 2014 |
Brain insulin signalling in metabolic homeostasis and disease T Scherer, K Sakamoto, C Buettner Nature Reviews Endocrinology 17 (8), 468-483, 2021 | 147 | 2021 |
Inhibition of cisplatin-induced lipid catabolism and weight loss by ghrelin in male mice JM Garcia, T Scherer, J Chen, B Guillory, A Nassif, V Papusha, ... Endocrinology 154 (9), 3118-3129, 2013 | 123 | 2013 |
Binge drinking induces whole-body insulin resistance by impairing hypothalamic insulin action C Lindtner, T Scherer, E Zielinski, N Filatova, M Fasshauer, NK Tonks, ... Science translational medicine 5 (170), 170ra14-170ra14, 2013 | 118 | 2013 |
Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis MT Hackl, C Fürnsinn, CM Schuh, M Krssak, F Carli, S Guerra, ... Nature communications 10 (1), 2717, 2019 | 103 | 2019 |
Insulin regulates hepatic triglyceride secretion and lipid content via signaling in the brain T Scherer, C Lindtner, J O’Hare, M Hackl, E Zielinski, A Freudenthaler, ... Diabetes 65 (6), 1511-1520, 2016 | 83 | 2016 |
Short term voluntary overfeeding disrupts brain insulin control of adipose tissue lipolysis T Scherer, C Lindtner, E Zielinski, J O'Hare, N Filatova, C Buettner Journal of biological chemistry 287 (39), 33061-33069, 2012 | 83 | 2012 |
CD8+ T cells induce cachexia during chronic viral infection H Baazim, M Schweiger, M Moschinger, H Xu, T Scherer, A Popa, ... Nature immunology 20 (6), 701-710, 2019 | 78 | 2019 |
Yin and Yang of hypothalamic insulin and leptin signaling in regulating white adipose tissue metabolism T Scherer, C Buettner Reviews in Endocrine and Metabolic Disorders 12, 235-243, 2011 | 77 | 2011 |
Intranasal insulin suppresses systemic but not subcutaneous lipolysis in healthy humans KA Iwen, T Scherer, M Heni, F Sayk, T Wellnitz, F Machleidt, H Preissl, ... The Journal of Clinical Endocrinology & Metabolism 99 (2), E246-E251, 2014 | 74 | 2014 |
Repurposing of bisphosphonates for the prevention and therapy of nonsmall cell lung and breast cancer A Stachnik, T Yuen, J Iqbal, M Sgobba, Y Gupta, P Lu, G Colaianni, Y Ji, ... Proceedings of the National Academy of Sciences 111 (50), 17995-18000, 2014 | 73 | 2014 |
Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis JD O’Hare, E Zieliński, B Cheng, T Scherer, C Buettner Diabetes 60 (4), 1055-1062, 2011 | 71 | 2011 |
Adipocyte glucocorticoid receptor deficiency attenuates aging-and HFD-induced obesity and impairs the feeding-fasting transition KM Mueller, K Hartmann, D Kaltenecker, S Vettorazzi, M Bauer, L Mauser, ... Diabetes 66 (2), 272-286, 2017 | 69 | 2017 |
Effects of insulin therapy on myocardial lipid content and cardiac geometry in patients with type-2 diabetes mellitus D Jankovic, Y Winhofer, M Promintzer-Schifferl, E Wohlschläger-Krenn, ... PloS one 7 (12), e50077, 2012 | 41 | 2012 |
Leptin increases hepatic triglyceride export via a vagal mechanism in humans M Metz, M Beghini, P Wolf, L Pfleger, M Hackl, M Bastian, A Freudenthaler, ... Cell metabolism 34 (11), 1719-1731. e5, 2022 | 36 | 2022 |
The dysregulation of the endocannabinoid system in diabesity—a tricky problem T Scherer, C Buettner Journal of molecular medicine 87, 663-668, 2009 | 36 | 2009 |