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Aaron N. Chang
Aaron N. Chang
Prime Medicine
Verified email at primemedicine.com
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Cited by
Year
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
KJ Rayner, FJ Sheedy, CC Esau, FN Hussain, RE Temel, S Parathath, ...
The Journal of clinical investigation 121 (7), 2921-2931, 2011
8062011
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways
BN Chau, C Xin, J Hartner, S Ren, AP Castano, G Linn, J Li, PT Tran, ...
Science translational medicine 4 (121), 121ra18-121ra18, 2012
6022012
Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215
SA Georges, MC Biery, S Kim, JM Schelter, J Guo, AN Chang, AL Jackson, ...
Cancer research 68 (24), 10105-10112, 2008
4172008
Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions
JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ...
Nature methods 14 (6), 573-576, 2017
3592017
MicroRNA miR-210 modulates cellular response to hypoxia through the MYC antagonist MNT
Z Zhang, H Sun, H Dai, R Walsh, M Imakura, J Schelter, J Burchard, X Dai, ...
Cell cycle 8 (17), 2756-2768, 2009
3492009
Functional genomics identifies therapeutic targets for MYC-driven cancer
M Toyoshima, HL Howie, M Imakura, RM Walsh, JE Annis, AN Chang, ...
Proceedings of the National Academy of Sciences 109 (24), 9545-9550, 2012
2912012
Non-coding transcription instructs chromatin folding and compartmentalization to dictate enhancer-promoter communication and T cell fate
T Isoda, AJ Moore, Z He, V Chandra, M Aida, M Denholtz, ...
Cell 171 (1), 103-119. e18, 2017
2672017
GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis
AN Chang, AB Cantor, Y Fujiwara, MB Lodish, S Droho, JD Crispino, ...
Proceedings of the National Academy of Sciences 99 (14), 9237-9242, 2002
2232002
Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development
Y Fujiwara, AN Chang, AM Williams, SH Orkin
Blood 103 (2), 583-585, 2004
1992004
MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1
TS Han, K Hur, G Xu, B Choi, Y Okugawa, Y Toiyama, H Oshima, ...
Gut 64 (2), 203-214, 2015
1592015
MicroRNA‐494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer
L Lim, A Balakrishnan, N Huskey, KD Jones, M Jodari, R Ng, G Song, ...
Hepatology 59 (1), 202-215, 2014
1372014
The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth
C Bossen, CS Murre, AN Chang, R Mansson, HR Rodewald, C Murre
Nature immunology 16 (7), 775-784, 2015
1322015
Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease
M Miyazaki, K Miyazaki, S Chen, M Itoi, M Miller, LF Lu, N Varki, ...
Nature immunology 15 (8), 767-776, 2014
1172014
An integrative multi-network and multi-classifier approach to predict genetic interactions
G Pandey, B Zhang, AN Chang, CL Myers, J Zhu, V Kumar, EE Schadt
PLoS computational biology 6 (9), e1000928, 2010
912010
Identification of SULF2 as a Novel Transcriptional Target of p53 by Use of Integrated Genomic Analyses
BN Chau, RL Diaz, MA Saunders, C Cheng, AN Chang, P Warrener, ...
Cancer research 69 (4), 1368-1374, 2009
522009
MYC dysregulates mitosis, revealing cancer vulnerabilities
J Rohrberg, D Van de Mark, M Amouzgar, JV Lee, M Taileb, A Corella, ...
Cell reports 30 (10), 3368-3382. e7, 2020
502020
Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification
CE Widjaja, JG Olvera, PJ Metz, AT Phan, JN Savas, G De Bruin, ...
The Journal of Clinical Investigation 127 (10), 3609-3623, 2017
472017
The transcription factor GATA2 regulates differentiation of brown adipocytes
J Tsai, Q Tong, G Tan, AN Chang, SH Orkin, GS Hotamisligil
EMBO reports 6 (9), 879-884, 2005
462005
The E–Id protein axis modulates the activities of the PI3K–AKT–mTORC1–Hif1a and c-myc/p19Arf pathways to suppress innate variant TFH cell development, thymocyte expansion, and …
M Miyazaki, K Miyazaki, S Chen, V Chandra, K Wagatsuma, Y Agata, ...
Genes & development 29 (4), 409-425, 2015
452015
Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition
A Banno, DA Garcia, ED van Baarsel, PJ Metz, K Fisch, CE Widjaja, ...
Oncotarget 7 (16), 21527, 2016
382016
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