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Barbara Bryant
Barbara Bryant
Constellation Pharmaceuticals
Verified email at constellationpharma.com
Title
Cited by
Cited by
Year
Targeting MYC dependence in cancer by inhibiting BET bromodomains
JA Mertz, AR Conery, BM Bryant, P Sandy, S Balasubramanian, DA Mele, ...
Proceedings of the National Academy of Sciences 108 (40), 16669-16674, 2011
12772011
Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma
JJ Keats, R Fonseca, M Chesi, R Schop, A Baker, WJ Chng, S Van Wier, ...
Cancer cell 12 (2), 131-144, 2007
12102007
Characterizing gene sets with FuncAssociate
GF Berriz, OD King, B Bryant, C Sander, FP Roth
Bioinformatics 19 (18), 2502-2504, 2003
5962003
Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
G Mulligan, C Mitsiades, B Bryant, F Zhan, WJ Chng, S Roels, E Koenig, ...
Hematology 63, 2005
4602005
Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families
MM Mahtani, E Widén, M Lehto, J Thomas, M McCarthy, J Brayer, ...
Nature genetics 14 (1), 90-94, 1996
4181996
Molecular dissection of hyperdiploid multiple myeloma by gene expression profiling
WJ Chng, S Kumar, S VanWier, G Ahmann, T Price-Troska, K Henderson, ...
Cancer research 67 (7), 2982-2989, 2007
3102007
ART 1 and pattern clustering
B Moore
Proceedings of the 1988 connectionist models summer school, 174-185, 1989
2991989
BET bromodomain inhibition suppresses TH17-mediated pathology
DA Mele, A Salmeron, S Ghosh, HR Huang, BM Bryant, JM Lora
Journal of experimental medicine 210 (11), 2181-2190, 2013
2542013
AACR-FDA-NCI Cancer Biomarkers Collaborative consensus report: advancing the use of biomarkers in cancer drug development
SN Khleif, JH Doroshow, WN Hait
Clinical Cancer Research 16 (13), 3299-3318, 2010
2292010
Identification of cervical cancer markers by cDNA and tissue microarrays
Y Chen, C Miller, R Mosher, X Zhao, J Deeds, M Morrissey, B Bryant, ...
Cancer research 63 (8), 1927, 2003
2142003
EZH2 inhibitor efficacy in non-Hodgkin’s lymphoma does not require suppression of H3K27 monomethylation
WD Bradley, S Arora, J Busby, S Balasubramanian, VS Gehling, ...
Chemistry & biology 21 (11), 1463-1475, 2014
1642014
A quantitative atlas of histone modification signatures from human cancer cells
G LeRoy, PA DiMaggio, EY Chan, BM Zee, MA Blanco, B Bryant, ...
Epigenetics & chromatin 6, 1-14, 2013
1502013
The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition
WJ Chng, E Braggio, G Mulligan, B Bryant, E Remstein, R Valdez, ...
Blood, The Journal of the American Society of Hematology 111 (3), 1603-1609, 2008
1452008
An alternative approach to ChIP-Seq normalization enables detection of genome-wide changes in histone H3 lysine 27 trimethylation upon EZH2 inhibition
B Egan, CC Yuan, ML Craske, P Labhart, GD Guler, D Arnott, TM Maile, ...
PloS one 11 (11), e0166438, 2016
1402016
Discovery, design, and optimization of isoxazole azepine BET inhibitors
VS Gehling, MC Hewitt, RG Vaswani, Y Leblanc, A Côté, CG Nasveschuk, ...
ACS medicinal chemistry letters 4 (9), 835-840, 2013
1242013
Methods for the identification, assessment, and treatment of patients with cancer therapy
BM Bryant, AI Damokosh, G Mulligan
US Patent 8,278,038, 2012
122*2012
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
AR Conery, RC Centore, A Neiss, PJ Keller, S Joshi, KL Spillane, ...
Elife 5, e10483, 2016
1112016
Pharmacological inhibition of the histone lysine demethylase KDM1A suppresses the growth of multiple acute myeloid leukemia subtypes
JP McGrath, KE Williamson, S Balasubramanian, S Odate, S Arora, ...
Cancer research 76 (7), 1975-1988, 2016
1022016
High-risk myeloma: A gene expression–based risk-stratification model for newly diagnosed multiple myeloma treated with high-dose therapy is predictive of outcome in relapsed …
F Zhan, B Barlogie, G Mulligan, JD Shaughnessy Jr, B Bryant
Blood 111 (2), 968-969, 2008
832008
Assessment of chromosomal alterations to predict clinical outcome of bortezomib treatment
BM Bryant, H Danaee, GJ Mulligan
US Patent App. 12/454,944, 2010
772010
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