| An integrated encyclopedia of DNA elements in the human genome. BE Bernstein, E Birney, I Dunham, ED Green, C Gunter, M Snyder Nature 489 (7414), 57, 2012 | 17212* | 2012 |
| Genome-wide maps of chromatin state in pluripotent and lineage-committed cells TS Mikkelsen, M Ku, DB Jaffe, B Issac, E Lieberman, G Giannoukos, ... Nature 448 (7153), 553-560, 2007 | 4972 | 2007 |
| In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state M Wernig, A Meissner, R Foreman, T Brambrink, M Ku, K Hochedlinger, ... Nature 448 (7151), 318-324, 2007 | 3583 | 2007 |
| Mapping and analysis of chromatin state dynamics in nine human cell types J Ernst, P Kheradpour, TS Mikkelsen, N Shoresh, LD Ward, CB Epstein, ... Nature 473 (7345), 43-49, 2011 | 3369 | 2011 |
| Dissecting direct reprogramming through integrative genomic analysis TS Mikkelsen, J Hanna, X Zhang, M Ku, M Wernig, P Schorderet, ... Nature 454 (7200), 49-55, 2008 | 1881 | 2008 |
| A user's guide to the encyclopedia of DNA elements (ENCODE) RM Myers, J Stamatoyannopoulos, M Snyder, I Dunham, RC Hardison, ... PLoS Biology 9 (4), e1001046, 2011 | 1484 | 2011 |
| Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains M Ku, RP Koche, E Rheinbay, EM Mendenhall, M Endoh, TS Mikkelsen, ... PLoS genetics 4 (10), e1000242, 2008 | 1176 | 2008 |
| Directly reprogrammed human neurons retain aging-associated transcriptomic signatures and reveal age-related nucleocytoplasmic defects J Mertens, ACM Paquola, M Ku, E Hatch, L Böhnke, S Ladjevardi, ... Cell stem cell 17 (6), 705-718, 2015 | 721 | 2015 |
| Jarid2 and PRC2, partners in regulating gene expression G Li, R Margueron, M Ku, P Chambon, BE Bernstein, D Reinberg Genes & development 24 (4), 368-380, 2010 | 549 | 2010 |
| GC-rich sequence elements recruit PRC2 in mammalian ES cells EM Mendenhall, RP Koche, T Truong, VW Zhou, B Issac, AS Chi, M Ku, ... PLoS genetics 6 (12), e1001244, 2010 | 507 | 2010 |
| Reprogramming factor expression initiates widespread targeted chromatin remodeling RP Koche, ZD Smith, M Adli, H Gu, M Ku, A Gnirke, BE Bernstein, ... Cell stem cell 8 (1), 96-105, 2011 | 438 | 2011 |
| An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia B Knoechel, JE Roderick, KE Williamson, J Zhu, JG Lohr, MJ Cotton, ... Nature genetics 46 (4), 364-370, 2014 | 400 | 2014 |
| SAM domain polymerization links subnuclear clustering of PRC1 to gene silencing K Isono, TA Endo, M Ku, D Yamada, R Suzuki, J Sharif, T Ishikura, ... Developmental cell 26 (6), 565-577, 2013 | 333 | 2013 |
| Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma VM Ravi, P Will, J Kueckelhaus, N Sun, K Joseph, H Salié, L Vollmer, ... Cancer cell 40 (6), 639-655. e13, 2022 | 274 | 2022 |
| Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons ST Schafer, ACM Paquola, S Stern, D Gosselin, M Ku, M Pena, TJM Kuret, ... Nature neuroscience 22 (2), 243-255, 2019 | 250 | 2019 |
| Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors G Lagna, MM Ku, PH Nguyen, NA Neuman, BN Davis, A Hata Journal of Biological Chemistry 282 (51), 37244-37255, 2007 | 212 | 2007 |
| H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions M Ku, RP Jaffe Jacob D, Koche, E Rheinbay, M Endoh, H Koseki, ... Genome Biology 13, R85, 2012 | 206 | 2012 |
| Negative regulation of the Wnt–β‐catenin pathway by the transcriptional repressor HBP1 EM Sampson, ZK Haque, MC Ku, SG Tevosian, C Albanese, RG Pestell, ... The EMBO journal, 2001 | 194 | 2001 |
| Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients J Mertens, JR Herdy, L Traxler, ST Schafer, JCM Schlachetzki, L Böhnke, ... Cell stem cell 28 (9), 1533-1548. e6, 2021 | 189 | 2021 |
| Differentiation of Inflammation-responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells S Renata, KC Vadodaria, BN Jaeger, M Arianna, S Lefcochilos-Fogelquist, ... Stem Cell Report 8 (6), 1757-1769, 2017 | 171 | 2017 |
Bradley BernsteinProfessor of Pathology, Harvard UniversityVerified email at broadinstitute.org
