Joachim Haupt
Joachim Haupt
Bestätigte E-Mail-Adresse bei biotec.tu-dresden.de
Titel
Zitiert von
Zitiert von
Jahr
PLIP: fully automated protein–ligand interaction profiler
S Salentin, S Schreiber, VJ Haupt, MF Adasme, M Schroeder
Nucleic acids research 43 (W1), W443-W447, 2015
7042015
Old friends in new guise: repositioning of known drugs with structural bioinformatics
VJ Haupt, M Schroeder
Briefings in bioinformatics 12 (4), 312-326, 2011
1472011
Drug promiscuity in PDB: protein binding site similarity is key
VJ Haupt, S Daminelli, M Schroeder
PLoS one 8 (6), e65894, 2013
1352013
Drug promiscuity in PDB: protein binding site similarity is key
VJ Haupt, S Daminelli, M Schroeder
PLoS one 8 (6), e65894, 2013
1352013
Polypharmacology rescored: Protein–ligand interaction profiles for remote binding site similarity assessment
S Salentin, VJ Haupt, S Daminelli, M Schroeder
Progress in biophysics and molecular biology 116 (2-3), 174-186, 2014
702014
Drug repositioning through incomplete bi-cliques in an integrated drug–target–disease network
S Daminelli, VJ Haupt, M Reimann, M Schroeder
Integrative Biology 4 (7), 778-788, 2012
522012
Pioneering topological methods for network-based drug–target prediction by exploiting a brain-network self-organization theory
C Durán, S Daminelli, JM Thomas, VJ Haupt, M Schroeder, ...
Briefings in bioinformatics 19 (6), 1183-1202, 2018
442018
New HSP27 inhibitors efficiently suppress drug resistance development in cancer cells
JC Heinrich, S Donakonda, VJ Haupt, P Lennig, Y Zhang, M Schroeder
Oncotarget 7 (42), 68156, 2016
362016
Chemoinformatic analysis of biologically active macrocycles
W Brandt, VJ Haupt, LA Wessjohann
Current topics in medicinal chemistry 10 (14), 1361-1379, 2010
352010
The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors
C Hutterer, S Hamilton, M Steingruber, I Zeitträger, H Bahsi, N Thuma, ...
Antiviral research 134, 130-143, 2016
252016
From malaria to cancer: Computational drug repositioning of amodiaquine using PLIP interaction patterns
S Salentin, MF Adasme, JC Heinrich, VJ Haupt, S Daminelli, Y Zhang, ...
Scientific reports 7 (1), 1-13, 2017
212017
Discovery of Mycobacterium tuberculosis InhA Inhibitors by Binding Sites Comparison and Ligands Prediction
T Štular, S Lešnik, K Rožman, J Schink, M Zdouc, A Ghysels, F Liu, ...
Journal of medicinal chemistry 59 (24), 11069-11078, 2016
212016
Computational drug repositioning by target hopping: A use case in chagas disease
V Joachim Haupt, J E Aguilar Uvalle, S Salentin, S Daminelli, F Leonhardt, ...
Current pharmaceutical design 22 (21), 3124-3134, 2016
132016
Backbone brackets and arginine tweezers delineate class I and class II aminoacyl tRNA synthetases
F Kaiser, S Bittrich, S Salentin, C Leberecht, VJ Haupt, S Krautwurst, ...
PLoS computational biology 14 (4), e1006101, 2018
122018
Genecloud: Secure cloud computing for biomedical research
M Beck, VJ Haupt, J Roy, J Moennich, R Jäkel, M Schroeder, Z Isik
Trusted Cloud Computing, 3-14, 2014
52014
Structure-based drug repositioning explains ibrutinib as VEGFR2 inhibitor
MF Adasme, D Parisi, K Van Belle, S Salentin, VJ Haupt, GS Jennings, ...
Plos one 15 (5), e0233089, 2020
42020
The structural basis of the genetic code: amino acid recognition by aminoacyl-tRNA synthetases
F Kaiser, S Krautwurst, S Salentin, VJ Haupt, C Leberecht, S Bittrich, ...
Scientific reports 10 (1), 1-17, 2020
32020
Computational drug repositioning for Chagas Disease using protein-ligand interaction profiling
A Juárez-Saldivar, M Schroeder, S Salentin, VJ Haupt, E Saavedra, ...
International journal of molecular sciences 21 (12), 4270, 2020
22020
Characterization of Amino Acid Recognition in Aminoacyl-tRNA Synthetases
F Kaiser, S Krautwurst, S Salentin, VJ Haupt, C Leberecht, S Bittrich, ...
BioRxiv, 606459, 2019
22019
In Silico Driven Prediction of MAPK14 Off-Targets Reveals Unrelated Proteins with High Accuracy
F Kaiser, MG Plach, C Leberecht, T Schubert, VJ Haupt
bioRxiv, 2020
12020
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