Dr Giles S.H. Yeo
Dr Giles S.H. Yeo
Principal Research Associate, University of Cambridge
Verified email at cam.ac.uk - Homepage
Cited by
Cited by
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
IS Farooqi, JM Keogh, GSH Yeo, EJ Lank, T Cheetham, S O'Rahilly
New England Journal of Medicine 348 (12), 1085-1095, 2003
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
T Gerken, CA Girard, YCL Tung, CJ Webby, V Saudek, KS Hewitson, ...
Science 318 (5855), 1469-1472, 2007
A frameshift mutation in MC4R associated with dominantly inherited human obesity
GSH Yeo, IS Farooqi, S Aminian, DJ Halsall, RG Stanhope, S O'Rahilly
Nature genetics 20 (2), 111-112, 1998
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency
IS Farooqi, GSH Yeo, JM Keogh, S Aminian, SA Jebb, G Butler, ...
The Journal of clinical investigation 106 (2), 271-279, 2000
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay
GSH Yeo, CCC Hung, J Rochford, J Keogh, J Gray, S Sivaramakrishnan, ...
Nature neuroscience 7 (11), 1187-1189, 2004
Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene
J Gray, GSH Yeo, JJ Cox, J Morton, ALR Adlam, JM Keogh, JA Yanovski, ...
Diabetes 55 (12), 3366-3371, 2006
The bigger picture of FTO—the first GWAS-identified obesity gene
RJF Loos, GSH Yeo
Nature Reviews Endocrinology 10 (1), 51-61, 2014
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism
G Medina-Gomez, SL Gray, L Yetukuri, K Shimomura, S Virtue, ...
PLoS genetics 3 (4), e64, 2007
Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension
EAB Azizan, H Poulsen, P Tuluc, J Zhou, MV Clausen, A Lieb, C Maniero, ...
Nature genetics 45 (9), 1055-1060, 2013
Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations
S Boissel, O Reish, K Proulx, H Kawagoe-Takaki, B Sedgwick, GSH Yeo, ...
The American Journal of Human Genetics 85 (1), 106-111, 2009
Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry
AM Habib, P Richards, LS Cairns, GJ Rogers, CAM Bannon, HE Parker, ...
Endocrinology 153 (7), 3054-3065, 2012
Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization
LF Gumy, GSH Yeo, YCL Tung, KH Zivraj, D Willis, G Coppola, BYH Lam, ...
Rna 17 (1), 85-98, 2011
A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular …
BG Challis, LE Pritchard, JWM Creemers, J Delplanque, JM Keogh, ...
Human molecular genetics 11 (17), 1997-2004, 2002
Serotonin activates the hypothalamic–pituitary–adrenal axis via serotonin 2C receptor stimulation
LK Heisler, N Pronchuk, K Nonogaki, L Zhou, J Raber, L Tung, GSH Yeo, ...
Journal of Neuroscience 27 (26), 6956-6964, 2007
Minireview: human obesity—lessons from monogenic disorders
S O’Rahilly, IS Farooqi, GSH Yeo, BG Challis
Endocrinology 144 (9), 3757-3764, 2003
Serotonin 5-HT2C Receptor Agonist Promotes Hypophagia via Downstream Activation of Melanocortin 4 Receptors
DD Lam, MJ Przydzial, SH Ridley, GSH Yeo, JJ Rochford, S O’Rahilly, ...
Endocrinology 149 (3), 1323-1328, 2008
Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs
KH Zivraj, YCL Tung, M Piper, L Gumy, JW Fawcett, GSH Yeo, CE Holt
Journal of Neuroscience 30 (46), 15464-15478, 2010
Unraveling the brain regulation of appetite: lessons from genetics
GSH Yeo, LK Heisler
Nature neuroscience 15 (10), 1343-1349, 2012
A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism
AJ de Smith, C Purmann, RG Walters, RJ Ellis, SE Holder, MM Van Haelst, ...
Human molecular genetics 18 (17), 3257-3265, 2009
Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms
GSH Yeo, EJ Lank, IS Farooqi, J Keogh, BG Challis, S O'Rahilly
Human molecular genetics 12 (5), 561-574, 2003
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