Michael P. Hefferan
Michael P. Hefferan
Associate Director, Voyager Therapeutics
Verified email at vygr.com
Title
Cited by
Cited by
Year
Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells
MA Israel, SH Yuan, C Bardy, SM Reyna, Y Mu, C Herrera, MP Hefferan, ...
Nature 482 (7384), 216-220, 2012
10902012
Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells
SH Yuan, J Martin, J Elia, J Flippin, RI Paramban, MP Hefferan, JG Vidal, ...
PloS one 6 (3), e17540, 2011
3512011
The Rheb–mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord
S Codeluppi, CI Svensson, MP Hefferan, F Valencia, MD Silldorff, ...
Journal of Neuroscience 29 (4), 1093-1104, 2009
1642009
Functional recovery in rats with ischemic paraplegia after spinal grafting of human spinal stem cells
D Cizkova, O Kakinohana, K Kucharova, S Marsala, K Johe, T Hazel, ...
Neuroscience 147 (2), 546-560, 2007
1052007
Human neural stem cell replacement therapy for amyotrophic lateral sclerosis by spinal transplantation
MP Hefferan, J Galik, O Kakinohana, G Sekerkova, C Santucci, S Marsala, ...
Public Library of Science 7 (8), e42614, 2012
1032012
REVIEW ARTILCE: Cell therapy and stem cells in animal models of motor neuron disorders
E Hedlund, MP Hefferan, M Marsala, O Isacson
European journal of neuroscience 26 (7), 1721-1737, 2007
912007
Coadministration of intrathecal strychnine and bicuculline effects synergistic allodynia in the rat: an isobolographic analysis
CW Loomis, H Khandwala, G Osmond, MP Hefferan
Journal of Pharmacology and Experimental Therapeutics 296 (3), 756-761, 2001
812001
The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers
N Emre, JG Vidal, J Elia, ED O'Connor, RI Paramban, MP Hefferan, ...
PloS one 5 (8), e12148, 2010
702010
Stem cells: comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery
JS Lunn, MP Hefferan, M Marsala, EL Feldman
Growth Factors 27 (3), 133-140, 2009
692009
Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: a qualitative and quantitative electrophysiological and histopathological study
O Kakinohana, MP Hefferan, S Nakamura, M Kakinohana, J Galik, ...
Neuroscience 141 (3), 1569-1583, 2006
652006
Analysis of dosing regimen and reproducibility of intraspinal grafting of human spinal stem cells in immunosuppressed minipigs
D Usvald, P Vodicka, J Hlucilova, R Prochazka, J Motlik, K Kuchorova, ...
Cell transplantation 19 (9), 1103-1122, 2010
552010
Inhibition of spinal prostaglandin synthesis early after L5/L6 nerve ligation prevents the development of prostaglandin-dependent and prostaglandin-independent allodynia in the rat
MP Hefferan, DD O'Rielly, CW Loomis
The Journal of the American Society of Anesthesiologists 99 (5), 1180-1188, 2003
542003
Spinal nerve injury activates prostaglandin synthesis in the spinal cord that contributes to early maintenance of tactile allodynia
MP Hefferan, P Carter, M Haley, CW Loomis
Pain 101 (1-2), 139-147, 2003
492003
Pig models of neurodegenerative disorders: Utilization in cell replacement‐based preclinical safety and efficacy studies
D Dolezalova, M Hruska‐Plochan, CR Bjarkam, JCH Sørensen, ...
Journal of Comparative Neurology 522 (12), 2784-2801, 2014
452014
Spinal astrocyte glutamate receptor 1 overexpression after ischemic insult facilitates behavioral signs of spasticity and rigidity
MP Hefferan, K Kucharova, K Kinjo, O Kakinohana, G Sekerkova, ...
Journal of Neuroscience 27 (42), 11179-11191, 2007
402007
Topical bicuculline to the rat spinal cord induces highly localized allodynia that is mediated by spinal prostaglandins
Z Zhang, MP Hefferan, CW Loomis
PAIN® 92 (3), 351-361, 2001
392001
In vivo gene knockdown in rat dorsal root ganglia mediated by self-complementary adeno-associated virus serotype 5 following intrathecal delivery
Q Xu, B Chou, B Fitzsimmons, A Miyanohara, V Shubayev, C Santucci, ...
PloS one 7 (3), e32581, 2012
352012
Spinal p38 mitogen‐activated protein kinase mediates allodynia induced by first‐degree burn in the rat
L Sorkin, CI Svensson, TL Jones‐Cordero, MP Hefferan, WM Campana
Journal of neuroscience research 87 (4), 948-955, 2009
352009
Optimization of immunosuppressive therapy for spinal grafting of human spinal stem cells in a rat model of ALS
MP Hefferan, K Johe, T Hazel, EL Feldman, JS Lunn, M Marsala
Cell transplantation 20 (8), 1153-1161, 2011
332011
Measurement of peripheral muscle resistance in rats with chronic ischemia-induced paraplegia or morphine-induced rigidity using a semi-automated computer-controlled muscle …
M Marsala, MP Hefferan, O Kakinohana, S Nakamura, J Marsala, ...
Journal of neurotrauma 22 (11), 1348-1361, 2005
322005
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