Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130 LM Judd, BM Alderman, M Howlett, A Shulkes, C Dow, J Moverley, D Grail, ... Gastroenterology 126 (1), 196-207, 2004 | 191 | 2004 |
Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivo LM Judd, TR Menheniott, H Ling, CB Jackson, M Howlett, A Kalantzis, ... PloS one 9 (5), e95993, 2014 | 104 | 2014 |
Cytokine signalling via gp130 in gastric cancer M Howlett, TR Menheniott, LM Judd, AS Giraud Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (11), 1623-1633, 2009 | 93 | 2009 |
The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development M Howlett, AS Giraud, H Lescesen, CB Jackson, A Kalantzis, IR Van Driel, ... Gastroenterology 136 (3), 967-977. e3, 2009 | 90 | 2009 |
Deregulated expression of connective tissue growth factor (CTGF/CCN2) is linked to poor outcome in human cancer JE Wells, M Howlett, CH Cole, UR Kees International journal of cancer 137 (3), 504-511, 2015 | 71 | 2015 |
Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130 M Howlett, LM Judd, B Jenkins, NL La Gruta, D Grail, M Ernst, AS Giraud Gastroenterology 129 (3), 1005-1018, 2005 | 63 | 2005 |
Comparative drug screening in NUT midline carcinoma AH Beesley, A Stirnweiss, E Ferrari, R Endersby, M Howlett, TW Failes, ... British journal of cancer 110 (5), 1189-1198, 2014 | 57 | 2014 |
IL-11 is a parietal cell cytokine that induces atrophic gastritis M Howlett, HV Chalinor, JN Buzzelli, N Nguyen, IR Van Driel, KM Bell, ... Gut 61 (10), 1398-1409, 2012 | 55 | 2012 |
New therapeutic opportunities from dissecting the pre-B leukemia bone marrow microenvironment LC Cheung, J Tickner, AM Hughes, P Skut, M Howlett, B Foley, ... Leukemia 32 (11), 2326-2338, 2018 | 37 | 2018 |
Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma R Endersby, J Whitehouse, A Pribnow, M Kuchibhotla, H Hii, B Carline, ... Science translational medicine 13 (577), eaba7401, 2021 | 31 | 2021 |
Cross‐fostering in Macropus eugenii leads to increased weight but not accelerated gastrointestinal maturation R Waite, A Giraud, J Old, M Howlett, G Shaw, K Nicholas, M Familari Journal of Experimental Zoology Part A: Comparative Experimental Biology 303 …, 2005 | 26 | 2005 |
Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis LC Cheung, DH Strickland, M Howlett, J Ford, AK Charles, KM Lyons, ... Haematologica 99 (7), 1149, 2014 | 24 | 2014 |
Cytokine signalling by gp130 regulates gastric mucosal healing after ulceration and, indirectly, antral tumour progression LM Judd, M Ulaganathan, M Howlett, AS Giraud The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 19 | 2009 |
ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma ER Jackson, RJ Duchatel, DE Staudt, ML Persson, A Mannan, S Yadavilli, ... Cancer research, OF1-OF17, 2023 | 18 | 2023 |
Defining the molecular features of radiation-induced glioma: A systematic review and meta-analysis JP Whitehouse, M Howlett, A Federico, M Kool, R Endersby, NG Gottardo Neuro-oncology advances 3 (1), vdab109, 2021 | 15 | 2021 |
Insights into the mechanisms of gastric adaptation to aspirin-induced injury: a role for regenerating protein but not trefoil peptides BM Alderman, M Ulaganathan, LM Judd, M Howlett, LM Parker, ... Laboratory investigation 83 (10), 1415-1425, 2003 | 14 | 2003 |
The role of CCN family genes in haematological malignancies JE Wells, M Howlett, LC Cheung, UR Kees Journal of cell communication and signaling 9 (3), 267-278, 2015 | 8 | 2015 |
Veliparib is an effective radiosensitizing agent in a preclinical model of medulloblastoma J Buck, PJC Dyer, H Hii, B Carline, M Kuchibhotla, J Byrne, M Howlett, ... Frontiers in molecular biosciences 8, 2021 | 7 | 2021 |
A Novel Orthotopic Patient-Derived Xenograft Model of Radiation-Induced Glioma Following Medulloblastoma JP Whitehouse, M Howlett, H Hii, C Mayoh, M Wong, P Barahona, ... Cancers 12 (10), 2937, 2020 | 7 | 2020 |
High expression of connective tissue growth factor accelerates dissemination of leukaemia JE Wells, M Howlett, HM Halse, J Heng, J Ford, LC Cheung, AL Samuels, ... Oncogene 35 (35), 4591-4600, 2016 | 7 | 2016 |