Jing Yang, Ph.D.
Jing Yang, Ph.D.
Dana-Farber Cancer Institute, Harvard Medical School
Verified email at dfci.harvard.edu
Cited by
Cited by
Th17 cells in autoimmune diseases
L Han, J Yang, X Wang, D Li, L Lv, B Li
Frontiers of medicine 9 (1), 10-19, 2015
Identification of the E3 deubiquitinase ubiquitin-specific peptidase 21 (USP21) as a positive regulator of the transcription factor GATA3
J Zhang, C Chen, X Hou, Y Gao, F Lin, J Yang, Z Gao, L Pan, L Tao, ...
Journal of Biological Chemistry 288 (13), 9373-9382, 2013
Inhibition of USP10 induces degradation of oncogenic FLT3
EL Weisberg, NJ Schauer, J Yang, I Lamberto, L Doherty, S Bhatt, ...
Nature chemical biology 13 (12), 1207-1215, 2017
Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs
S Ma, X Wan, Z Deng, L Shi, C Hao, Z Zhou, C Zhou, Y Fang, J Liu, ...
Journal of Experimental Medicine 214 (5), 1471-1491, 2017
Molecular mechanisms underlying the regulation and functional plasticity of FOXP3+ regulatory T cells
Y Gao, F Lin, J Su, Z Gao, Y Li, J Yang, Z Deng, B Liu, A Tsun, B Li
Genes & Immunity 13 (1), 1-13, 2012
Cutting edge: ubiquitin-specific protease 4 promotes Th17 cell function under inflammation by deubiquitinating and stabilizing RORγt
J Yang, P Xu, L Han, Z Guo, X Wang, Z Chen, J Nie, S Yin, M Piccioni, ...
The Journal of Immunology 194 (9), 4094-4097, 2015
The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor γt (RORγt) in Th17 cells
L Han, J Yang, X Wang, Q Wu, S Yin, Z Li, J Zhang, Y Xing, Z Chen, ...
Journal of Biological Chemistry 289 (37), 25546-25555, 2014
Mixed lineage leukemia 5 (MLL5) protein stability is cooperatively regulated by O-GlcNac transferase (OGT) and ubiquitin specific protease 7 (USP7)
X Ding, W Jiang, P Zhou, L Liu, X Wan, X Yuan, X Wang, M Chen, J Chen, ...
PloS one 10 (12), e0145023, 2015
Reciprocal regulation of RORγt acetylation and function by p300 and HDAC1
Q Wu, J Nie, Y Gao, P Xu, Q Sun, J Yang, L Han, Z Chen, X Wang, L Lv, ...
Scientific reports 5 (1), 1-11, 2015
TRAF5-mediated Lys-63-linked polyubiquitination plays an essential role in positive regulation of RORγt in promoting IL-17A expression
X Wang, J Yang, L Han, K Zhao, Q Wu, L Bao, Z Li, L Lv, B Li
Journal of Biological Chemistry 290 (48), 29086-29094, 2015
Characterization of midostaurin as a dual inhibitor of FLT3 and SYK and potentiation of FLT3 inhibition against FLT3-ITD-driven leukemia harboring activated SYK kinase
EL Weisberg, A Puissant, R Stone, M Sattler, SJ Buhrlage, J Yang, ...
Oncotarget 8 (32), 52026, 2017
Comparison of effects of midostaurin, crenolanib, quizartinib, gilteritinib, sorafenib and BLU‐285 on oncogenic mutants of KIT, CBL and FLT3 in haematological malignancies
E Weisberg, C Meng, AE Case, M Sattler, HL Tiv, PC Gokhale, ...
British journal of haematology 187 (4), 488-501, 2019
Effects of the multi‐kinase inhibitor midostaurin in combination with chemotherapy in models of acute myeloid leukaemia
E Weisberg, C Meng, AE Case, HL Tiv, PC Gokhale, SJ Buhrlage, J Yang, ...
Journal of cellular and molecular medicine 24 (5), 2968-2980, 2020
The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation
J Yang, P Wei, J Barbi, Q Huang, E Yang, Y Bai, J Nie, Y Gao, J Tao, Y Lu, ...
EMBO reports 21 (9), e50308, 2020
Inhibition of the deubiquitinase USP10 induces degradation of SYK
J Yang, C Meng, E Weisberg, A Case, I Lamberto, RS Magin, S Adamia, ...
British journal of cancer 122 (8), 1175-1184, 2020
Inhibition of USP10 Induces Degradation of Oncogenic FLT3: a novel approach to therapy of leukemia
S Buhrlage, E Weisberg, N Schauer, J Yang, I Lamberto, L Doherty, ...
Blood, The Journal of the American Society of Hematology 128 (22), 524-524, 2016
Target class platform accelerates deubiquitinase early discovery efforts
S Buhrlage, E Weisberg, N Schauer, X Liu, J Yang, I Lamberto
Abstract PR04: Degradation of leukemia oncogenes: A novel approach to therapy of leukemia
S Buhrlage, E Weisberg, I Lamberto, J Yang, N Schauer, M Sattler, ...
Clinical Cancer Research 23 (24 Supplement), PR04-PR04, 2017
Degradation of leukemia oncogenes: A novel approach to therapy of leukemia.
S Buhrlage, E Weisberg, I Lamberto, J Yang, N Schauer, M Sattler, ...
CLINICAL CANCER RESEARCH 23 (24), 28-29, 2017
Use of ubiquitination pathway-related factors in regulating function of t helper cell
李斌, 杨静, 韩磊, 林芳, 李孔晨, 李丹
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