The genetic landscape of a cell M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ... science 327 (5964), 425-431, 2010 | 2540 | 2010 |
A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), aaf1420, 2016 | 1315 | 2016 |
A community effort to assess and improve drug sensitivity prediction algorithms JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ... Nature biotechnology 32 (12), 1202-1212, 2014 | 798 | 2014 |
Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ... G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017 | 538 | 2017 |
Systematic exploration of essential yeast gene function with temperature-sensitive mutants Z Li, FJ Vizeacoumar, S Bahr, J Li, J Warringer, FS Vizeacoumar, R Min, ... Nature biotechnology 29 (4), 361-367, 2011 | 454 | 2011 |
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale A Baryshnikova, M Costanzo, Y Kim, H Ding, J Koh, K Toufighi, JY Youn, ... Nature methods 7 (12), 1017-1024, 2010 | 437 | 2010 |
Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae T Reguly, A Breitkreutz, L Boucher, BJ Breitkreutz, GC Hon, CL Myers, ... Journal of biology 5, 1-28, 2006 | 411 | 2006 |
Systematic exploration of synergistic drug pairs M Cokol, HN Chua, M Tasan, B Mutlu, ZB Weinstein, Y Suzuki, ME Nergiz, ... Molecular systems biology 7 (1), 544, 2011 | 367 | 2011 |
A community computational challenge to predict the activity of pairs of compounds M Bansal, J Yang, C Karan, MP Menden, JC Costello, H Tang, G Xiao, ... Nature biotechnology 32 (12), 1213-1222, 2014 | 332 | 2014 |
Exploring the functional landscape of gene expression: directed search of large microarray compendia MA Hibbs, DC Hess, CL Myers, C Huttenhower, K Li, OG Troyanskaya Bioinformatics 23 (20), 2692-2699, 2007 | 307 | 2007 |
A critical assessment of Mus musculusgene function prediction using integrated genomic evidence L Peña-Castillo, M Tasan, CL Myers, H Lee, T Joshi, C Zhang, Y Guan, ... Genome biology 9, 1-19, 2008 | 298 | 2008 |
Systematic analysis of complex genetic interactions E Kuzmin, B VanderSluis, W Wang, G Tan, R Deshpande, Y Chen, M Usaj, ... Science 360 (6386), eaao1729, 2018 | 290 | 2018 |
Discovery of biological networks from diverse functional genomic data CL Myers, D Robson, A Wible, MA Hibbs, C Chiriac, CL Theesfeld, ... Genome biology 6, 1-16, 2005 | 262 | 2005 |
Finding function: evaluation methods for functional genomic data CL Myers, DR Barrett, MA Hibbs, C Huttenhower, OG Troyanskaya BMC genomics 7, 1-15, 2006 | 258 | 2006 |
Epigenetic and genetic influences on DNA methylation variation in maize populations SR Eichten, R Briskine, J Song, Q Li, R Swanson-Wagner, PJ Hermanson, ... The Plant Cell 25 (8), 2783-2797, 2013 | 256 | 2013 |
Synthetic genetic array (SGA) analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe A Baryshnikova, M Costanzo, S Dixon, FJ Vizeacoumar, CL Myers, ... Methods in enzymology 470, 145-179, 2010 | 253 | 2010 |
An integrated approach to characterize genetic interaction networks in yeast metabolism B Szappanos, K Kovács, B Szamecz, F Honti, M Costanzo, ... Nature genetics 43 (7), 656-662, 2011 | 248 | 2011 |
Using networks to measure similarity between genes: association index selection JIF Bass, A Diallo, J Nelson, JM Soto, CL Myers, AJM Walhout Nature methods 10 (12), 1169-1176, 2013 | 246 | 2013 |
Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes SJ Dixon, Y Fedyshyn, JLY Koh, TSK Prasad, C Chahwan, G Chua, ... Proceedings of the National Academy of Sciences 105 (43), 16653-16658, 2008 | 218 | 2008 |
Accurate detection of aneuploidies in array CGH and gene expression microarray data CL Myers, MJ Dunham, SY Kung, OG Troyanskaya Bioinformatics 20 (18), 3533-3543, 2004 | 217 | 2004 |