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Flemming Steen Jørgensen
Flemming Steen Jørgensen
Professor, Department of Drug Design and Pharmacology, University of Copenhagen
Bestätigte E-Mail-Adresse bei sund.ku.dk
Titel
Zitiert von
Zitiert von
Jahr
Study on the binding of Thioflavin T to β-sheet-rich and non-β-sheet cavities
M Groenning, L Olsen, M van de Weert, JM Flink, S Frokjaer, ...
Journal of structural biology 158 (3), 358-369, 2007
2982007
GABAA receptor agonists, partial agonists, and antagonists. Design and therapeutic prospects
P Krogsgaard-Larsen, B Frølund, FS Joergensen, A Schousboe
Journal of medicinal chemistry 37 (16), 2489-2505, 1994
1601994
Prediction methods and databases within chemoinformatics: emphasis on drugs and drug candidates
SÓ Jónsdóttir, FS Jørgensen, S Brunak
Bioinformatics 21 (10), 2145-2160, 2005
1452005
Evaluation and comparison of 3D-QSAR CoMSIA models for CDK1, CDK5, and GSK-3 inhibition by paullones
C Kunick, K Lauenroth, K Wieking, X Xie, C Schultz, R Gussio, ...
Journal of Medicinal Chemistry 47 (1), 22-36, 2004
1382004
A new concept for multidimensional selection of ligand conformations (MultiSelect) and multidimensional scoring (MultiScore) of protein− ligand binding affinities
GE Terp, BN Johansen, IT Christensen, FS Jørgensen
Journal of medicinal chemistry 44 (14), 2333-2343, 2001
1382001
Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques
P Vasanthanathan, O Taboureau, C Oostenbrink, NPE Vermeulen, ...
Drug Metabolism and Disposition 37 (3), 658-664, 2009
1172009
hERG classification model based on a combination of support vector machine method and GRIND descriptors
Q Li, FS Jørgensen, T Oprea, S Brunak, O Taboureau
Molecular pharmaceutics 5 (1), 117-127, 2008
1132008
Prediction of cytochrome P450 mediated metabolism
L Olsen, C Oostenbrink, FS Jørgensen
Advanced drug delivery reviews 86, 61-71, 2015
1112015
Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter
J Andersen, L Olsen, KB Hansen, O Taboureau, FS Jørgensen, ...
Journal of Biological Chemistry 285 (3), 2051-2063, 2010
1082010
Structural differences of matrix metalloproteinases with potential implications for inhibitor selectivity examined by the GRID/CPCA approach
GE Terp, G Cruciani, IT Christensen, FS Jørgensen
Journal of medicinal chemistry 45 (13), 2675-2684, 2002
1052002
Prediction of pH-dependent aqueous solubility of druglike molecules
NT Hansen, I Kouskoumvekaki, FS Jørgensen, S Brunak, SO Jonsdottir
Journal of chemical information and modeling 46 (6), 2601-2609, 2006
1002006
Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia
AM Buhl, J Jurlander, FS Jørgensen, AM Ottesen, JB Cowland, ...
Blood 107 (7), 2904-2911, 2006
1002006
Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands
P Vasanthanathan, J Hritz, O Taboureau, L Olsen, F Steen Jørgensen, ...
Journal of chemical information and modeling 49 (1), 43-52, 2009
882009
Recent advances in GABA agonists, antagonists and uptake inhibitors: structure–activity relationships and therapeutic potential
P KROGSGAARD-LARSEN, H HJEDS, E FALCH, FS JØRGENSEN, ...
Advances in drug research 17, 381-456, 1988
851988
New leads of metallo-β-lactamase inhibitors from structure-based pharmacophore design
L Olsen, S Jost, HW Adolph, I Pettersson, L Hemmingsen, FS Jørgensen
Bioorganic & medicinal chemistry 14 (8), 2627-2635, 2006
692006
SMARTCyp 3.0: enhanced cytochrome P450 site-of-metabolism prediction server
L Olsen, M Montefiori, KP Tran, FS Jørgensen
Bioinformatics 35 (17), 3174-3175, 2019
682019
Solvent diversity in polymorph screening
M Allesø, F Van Den Berg, C Cornett, FS Jørgensen, B Halling-Sørensen, ...
Journal of pharmaceutical sciences 97 (6), 2145-2159, 2008
682008
Primary structure and conformational analysis of peptide methionine—tyrosine, a peptide related to neuropeptide Y and peptide YY isolated from lamprey intestine
JM CONLON, B Bjørnholm, FS Jørgensen, JH Youson, TW Schwartz
European journal of biochemistry 199 (2), 293-298, 1991
621991
Cyclynes. Part 5. Pericyclynes:" exploded cycloalkanes" with unusual orbital interactions and conformational properties. MM2 and STO-3G calculations, x-ray crystal structures …
KN Houk, LT Scott, NG Rondan, DC Spellmeyer, G Reinhardt, JL Hyun, ...
Journal of the American Chemical Society 107 (23), 6556-6562, 1985
621985
Homology modelling of the GABA transporter and analysis of tiagabine binding
S Skovstrup, O Taboureau, H Bräuner‐Osborne, FS Jørgensen
ChemMedChem 5 (7), 986-1000, 2010
612010
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