Kelly D. Smith
Kelly D. Smith
Professor of Pathology
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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
F Hayashi, KD Smith, A Ozinsky, TR Hawn, EC Yi, DR Goodlett, JK Eng, ...
Nature 410 (6832), 1099-1103, 2001
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
A Ozinsky, DM Underhill, JD Fontenot, AM Hajjar, KD Smith, CB Wilson, ...
Proceedings of the National Academy of Sciences 97 (25), 13766-13771, 2000
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
TH Flo, KD Smith, S Sato, DJ Rodriguez, MA Holmes, RK Strong, S Akira, ...
Nature 432 (7019), 917-921, 2004
The evolution of vertebrate Toll-like receptors
JC Roach, G Glusman, L Rowen, A Kaur, MK Purcell, KD Smith, LE Hood, ...
Proceedings of the National Academy of Sciences 102 (27), 9577-9582, 2005
Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages
DM Underhill, A Ozinsky, KD Smith, A Aderem
Proceedings of the National Academy of Sciences 96 (25), 14459-14463, 1999
Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility
KD Smith, E Andersen-Nissen, F Hayashi, K Strobe, MA Bergman, ...
Nature immunology 4 (12), 1247-1253, 2003
Evasion of Toll-like receptor 5 by flagellated bacteria
E Andersen-Nissen, KD Smith, KL Strobe, SLR Barrett, BT Cookson, ...
Proceedings of the national academy of sciences 102 (26), 9247-9252, 2005
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease
TR Hawn, A Verbon, KD Lettinga, LP Zhao, SS Li, RJ Laws, SJ Skerrett, ...
The Journal of experimental medicine 198 (10), 1563-1572, 2003
The Toll-like receptor 5 stimulus bacterial flagellin induces maturation and chemokine production in human dendritic cells
TK Means, F Hayashi, KD Smith, A Aderem, AD Luster
The Journal of Immunology 170 (10), 5165-5175, 2003
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2
MA Fischbach, H Lin, L Zhou, Y Yu, RJ Abergel, DR Liu, KN Raymond, ...
Proceedings of the National Academy of Sciences 103 (44), 16502-16507, 2006
TLR4 links podocytes with the innate immune system to mediate glomerular injury
MC Banas, B Banas, KL Hudkins, TA Wietecha, M Iyoda, E Bock, ...
Journal of the American Society of Nephrology 19 (4), 704-713, 2008
Cutting edge: Tlr5−/− mice are more susceptible to Escherichia coli urinary tract infection
E Andersen-Nissen, TR Hawn, KD Smith, A Nachman, AE Lampano, ...
The Journal of immunology 178 (8), 4717-4720, 2007
A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin
E Andersen-Nissen, KD Smith, R Bonneau, RK Strong, A Aderem
The Journal of experimental medicine 204 (2), 393-403, 2007
Conservation of Toll-like receptor signaling pathways in teleost fish
MK Purcell, KD Smith, A Aderem, L Hood, JR Winton, JC Roach
Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 1 (1 …, 2006
Multicenter clinicopathologic correlation of kidney biopsies performed in COVID-19 patients presenting with acute kidney injury or proteinuria
S Akilesh, CC Nast, M Yamashita, K Henriksen, V Charu, ML Troxell, ...
American Journal of Kidney Diseases 77 (1), 82-93. e1, 2021
Low HLA-C expression at cell surfaces correlates with increased turnover of heavy chain mRNA.
JA McCutcheon, J Gumperz, KD Smith, CT Lutz, P Parham
The Journal of experimental medicine 181 (6), 2085-2095, 1995
Human pulmonary surfactant protein D binds the extracellular domains of Toll-like receptors 2 and 4 through the carbohydrate recognition domain by a mechanism different from …
M Ohya, C Nishitani, H Sano, C Yamada, H Mitsuzawa, T Shimizu, T Saito, ...
Biochemistry 45 (28), 8657-8664, 2006
Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use
KD Smith, LE Wrenshall, RF Nicosia, R Pichler, CL Marsh, CE Alpers, ...
Journal of the American Society of Nephrology 14 (4), 1037-1045, 2003
Humanized nonobese diabetic-scid IL2rγnull mice are susceptible to lethal Salmonella Typhi infection
SJ Libby, MA Brehm, DL Greiner, LD Shultz, M McClelland, KD Smith, ...
Proceedings of the National Academy of Sciences 107 (35), 15589-15594, 2010
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
AC Walls, MC Miranda, A Schäfer, MN Pham, A Greaney, ...
Cell 184 (21), 5432-5447. e16, 2021
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