Chemical activation of the mechanotransduction channel Piezo1 R Syeda, J Xu, AE Dubin, B Coste, J Mathur, T Huynh, J Matzen, J Lao, ... elife 4, e07369, 2015 | 569 | 2015 |
Targeting Plasmodium PI(4)K to eliminate malaria CW McNamara, MCS Lee, CS Lim, SH Lim, J Roland, A Nagle, O Simon, ... Nature 504 (7479), 248-253, 2013 | 433 | 2013 |
Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries J Li, SP Lim, D Beer, V Patel, D Wen, C Tumanut, DC Tully, JA Williams, ... Journal of Biological Chemistry 280 (31), 28766-28774, 2005 | 293 | 2005 |
Dendrimers at surfaces and interfaces: chemistry and applications DC Tully, JMJ Fréchet Chemical Communications, 1229-1239, 2001 | 287 | 2001 |
Discovery of tropifexor (LJN452), a highly potent non-bile acid FXR agonist for the treatment of cholestatic liver diseases and nonalcoholic steatohepatitis (NASH) DC Tully, PV Rucker, D Chianelli, J Williams, A Vidal, PB Alper, D Mutnick, ... Journal of medicinal chemistry 60 (24), 9960-9973, 2017 | 217 | 2017 |
Apparatus and methods to process substrate surface features J Mainquist, B Geierstanger, D Tully US Patent App. 10/704,204, 2004 | 182 | 2004 |
PNA-encoded protease substrate microarrays N Winssinger, R Damoiseaux, DC Tully, BH Geierstanger, K Burdick, ... Chemistry & biology 11 (10), 1351-1360, 2004 | 170 | 2004 |
KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission KL Kuhen, AK Chatterjee, M Rottmann, K Gagaring, R Borboa, ... Antimicrobial agents and chemotherapy 58 (9), 5060-5067, 2014 | 163 | 2014 |
Electrically conducting dendrimers LL Miller, RG Duan, DC Tully, DA Tomalia Journal of the American Chemical Society 119 (5), 1005-1010, 1997 | 151 | 1997 |
A novel multifunctional labeling reagent for enhanced protein characterization with mass spectrometry EC Peters, DM Horn, DC Tully, A Brock Rapid Communications in Mass Spectrometry 15 (24), 2387-2392, 2001 | 147 | 2001 |
Dendrimer‐based self‐assembled monolayers as resists for scanning probe lithography DC Tully, K Wilder, JMJ Fréchet, AR Trimble, CF Quate Advanced Materials 11 (4), 314-318, 1999 | 134 | 1999 |
Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease K Coote, HC Atherton-Watson, R Sugar, A Young, A MacKenzie-Beevor, ... Journal of Pharmacology and Experimental Therapeutics 329 (2), 764-774, 2009 | 117 | 2009 |
Imidazolopiperazines: hit to lead optimization of new antimalarial agents T Wu, A Nagle, K Kuhen, K Gagaring, R Borboa, C Francek, Z Chen, ... Journal of medicinal chemistry 54 (14), 5116-5130, 2011 | 116 | 2011 |
Dendrimers with thermally labile end groups: an alternative approach to chemically amplified resist materials designed for sub‐100 nm lithography DC Tully, AR Trimble, JMJ Frechet Advanced Materials 12 (15), 1118-1122, 2000 | 109 | 2000 |
Imidazolopiperazines: lead optimization of the second-generation antimalarial agents A Nagle, T Wu, K Kuhen, K Gagaring, R Borboa, C Francek, Z Chen, ... Journal of medicinal chemistry 55 (9), 4244-4273, 2012 | 104 | 2012 |
Biochemical characterization of prostasin, a channel activating protease A Shipway, H Danahay, JA Williams, DC Tully, BJ Backes, JL Harris Biochemical and biophysical research communications 324 (2), 953-963, 2004 | 99 | 2004 |
Tropifexor‐mediated abrogation of steatohepatitis and fibrosis is associated with the antioxidative gene expression profile in rodents ED Hernandez, L Zheng, Y Kim, B Fang, B Liu, RA Valdez, WF Dietrich, ... Hepatology communications 3 (8), 1085-1097, 2019 | 84 | 2019 |
Nidufexor (LMB763), a novel FXR modulator for the treatment of nonalcoholic steatohepatitis D Chianelli, PV Rucker, J Roland, DC Tully, J Nelson, X Liu, B Bursulaya, ... Journal of medicinal chemistry 63 (8), 3868-3880, 2020 | 83 | 2020 |
Synthesis and preparation of ionically bound dendrimer monolayers and application toward scanning probe lithography DC Tully, AR Trimble, JMJ Frechet, K Wilder, CF Quate Chemistry of materials 11 (10), 2892-2898, 1999 | 81 | 1999 |
Dendrimers peripherally modified with anion radicals that form π-dimers and π-stacks I Tabakovic, LL Miller, RG Duan, DC Tully, DA Tomalia Chemistry of materials 9 (3), 736-745, 1997 | 76 | 1997 |