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yvon Trottier
yvon Trottier
Institut de Genetique et de Biologie moleculaire et cellulaire
Verified email at igbmc.fr
Title
Cited by
Cited by
Year
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, ...
Cell 87 (3), 493-506, 1996
35671996
Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3
HL Paulson, MK Perez, Y Trottier, JQ Trojanowski, SH Subramony, ...
Neuron 19 (2), 333-344, 1997
10081997
Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats
G Imbert, F Saudou, G Yvert, D Devys, Y Trottier, JM Garnier, C Weber, ...
Nature genetics 14 (3), 285-291, 1996
10031996
Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes
V Campuzano, L Montermini, Y Lutz, L Cova, C Hindelang, S Jiralerspong, ...
Human molecular genetics 6 (11), 1771-1780, 1997
8881997
Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias
Y Trottier, Y Lutz, G Stevanin, G Imbert, D Devys, G Cancel, F Saudou, ...
Nature 378 (6555), 403-406, 1995
7881995
Phenotypic characterization of individuals with 30–40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals …
DC Rubinsztein, J Leggo, R Coles, E Almqvist, V Biancalana, ...
American journal of human genetics 59 (1), 16, 1996
7021996
Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form
Y Trottier, D Devys, G Imbert, F Saudou, I An, Y Lutz, C Weber, Y Agid, ...
Nature genetics 10 (1), 104-110, 1995
5661995
Proteases acting on mutant huntingtin generate cleaved products that differentially build up cytoplasmic and nuclear inclusions
A Lunkes, KS Lindenberg, L Ben-Haı̈em, C Weber, D Devys, ...
Molecular cell 10 (2), 259-269, 2002
4942002
Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions
M Holmberg, C Duyckaerts, A Dürr, G Cancel, I Gourfinkel-An, P Damier, ...
Human molecular genetics 7 (5), 913-918, 1998
4291998
Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease
C Landles, K Sathasivam, A Weiss, B Woodman, H Moffitt, S Finkbeiner, ...
Journal of Biological Chemistry 285 (12), 8808-8823, 2010
3532010
Instability of CAG repeats in Huntington's disease: relation to parental transmission and age of onset.
Y Trottier, V Biancalana, JL Mandel
Journal of medical genetics 31 (5), 377-382, 1994
2961994
An isoform of ataxin‐3 accumulates in the nucleus of neuronal cells in affected brain regions of SCA3 patients
T Schmidt, GB Landwehrmeyer, I Schmitt, Y Trottier, G Auburger, ...
Brain pathology 8 (4), 669-679, 1998
2561998
Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction
D Helmlinger, S Hardy, G Abou-Sleymane, A Eberlin, AB Bowman, ...
PLoS biology 4 (3), e67, 2006
1872006
Solution structure of polyglutamine tracts in GST-polyglutamine fusion proteins
L Masino, G Kelly, K Leonard, Y Trottier, A Pastore
Febs Letters 513 (2-3), 267-272, 2002
1852002
Domain architecture of the polyglutamine protein ataxin‐3: a globular domain followed by a flexible tail
L Masino, V Musi, RP Menon, P Fusi, G Kelly, TA Frenkiel, Y Trottier, ...
FEBS letters 549 (1-3), 21-25, 2003
1582003
Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice
AV Goula, BR Berquist, DM Wilson III, VC Wheeler, Y Trottier, K Merienne
PLoS genetics 5 (12), e1000749, 2009
1572009
Heterogeneous intracellular localization and expression of ataxin-3
Y Trottier, G Cancel, I An-Gourfinkel, Y Lutz, C Weber, A Brice, E Hirsch, ...
Neurobiology of disease 5 (5), 335-347, 1998
1421998
An expanded CAG repeat sequence in spinocerebellar ataxia type 7.
K Lindblad, ML Savontaus, G Stevanin, M Holmberg, K Digre, C Zander, ...
Genome Research 6 (10), 965-971, 1996
1321996
High Level Expression of Expanded Full-length Ataxin-3 In Vitro Causes Cell Death and Formation of Intranuclear Inclusions in Neuronal Cells
BO Evert, U Wüllner, JB Schulz, M Weller, P Groscurth, Y Trottier, A Brice, ...
Human molecular genetics 8 (7), 1169-1176, 1999
1031999
Pathogenic and non-pathogenic polyglutamine tracts have similar structural properties: towards a length-dependent toxicity gradient
FAC Klein, A Pastore, L Masino, G Zeder-Lutz, H Nierengarten, ...
Journal of molecular biology 371 (1), 235-244, 2007
1022007
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